M
Matthew S. Joens
Researcher at Washington University in St. Louis
Publications - 25
Citations - 2344
Matthew S. Joens is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Light sheet fluorescence microscopy & Golgi apparatus. The author has an hindex of 13, co-authored 25 publications receiving 1756 citations. Previous affiliations of Matthew S. Joens include University of Washington & TESCAN.
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Journal ArticleDOI
Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
Megumi Hatori,Christopher Vollmers,Amir Zarrinpar,Amir Zarrinpar,Luciano DiTacchio,Eric A. Bushong,Shubhroz Gill,Mathias Leblanc,Amandine Chaix,Matthew S. Joens,James A. J. Fitzpatrick,Mark H. Ellisman,Satchidananda Panda +12 more
TL;DR: Mice under tRF consume equivalent calories from HFD as those with ad lib access yet are protected against obesity, hyperinsulinemia, hepatic steatosis, and inflammation and have improved motor coordination.
Journal ArticleDOI
Ubiquitin facilitates a quality-control pathway that removes damaged chloroplasts
Jesse D. Woodson,Matthew S. Joens,Andrew B. Sinson,Jonathan Gilkerson,Patrice A. Salomé,Detlef Weigel,James A. J. Fitzpatrick,Joanne Chory,Joanne Chory +8 more
TL;DR: A signal is identified that leads to the targeted removal of ROS-overproducing chloroplasts in the chloroplast, revealing how cells balance inherently stressful energy production with organelle turnover.
Journal ArticleDOI
Helium Ion Microscopy (HIM) for the imaging of biological samples at sub-nanometer resolution
Matthew S. Joens,Chuong Huynh,James M. Kasuboski,David C. Ferranti,Yury J. Sigal,Fabian Zeitvogel,Martin Obst,Claus Burkhardt,Kevin P. Curran,Sreekanth H. Chalasani,Lewis Stern,Bernhard Goetze,James A. J. Fitzpatrick +12 more
TL;DR: The advantages of the Helium Ion Microscope for imaging biological surfaces as well as compare and contrast the effects of sample preparation techniques and their consequences on sub-nanometer ultrastructure are demonstrated.
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Catheterization alters bladder ecology to potentiate Staphylococcus aureus infection of the urinary tract
Jennifer N. Walker,Ana L. Flores-Mireles,Chloe L. Pinkner,Henry L. Schreiber,Matthew S. Joens,Alyssa M. Park,Aaron M. Potretzke,Tyler M. Bauman,Jerome S. Pinkner,James A. J. Fitzpatrick,Alana Desai,Michael G. Caparon,Scott J. Hultgren +12 more
TL;DR: It is suggested that catheterization alters the urinary tract environment to promote MRSA CAUTI pathogenesis by inducing the release of Fg, which the pathogen enhances to persist in the urinary tracts despite the host’s robust immune response.
Journal ArticleDOI
Characterization of a Mycobacterium tuberculosis Nanocompartment and Its Potential Cargo Proteins
Heidi Contreras,Matthew S. Joens,Lisa M. McMath,Vincent P. Le,Michael V. Tullius,Jacqueline M. Kimmey,Neda Bionghi,Marcus A. Horwitz,James A. J. Fitzpatrick,Celia W. Goulding +9 more
TL;DR: It is shown by co-purification and electron microscopy that mycobacteria via Mt-Enc can encapsulate Mt-DyP, Mt-BfrB, and Mt-FolB, which may aid in detoxification of the local environment to ensure long term survival.