C
Cleo L. Bishop
Researcher at Queen Mary University of London
Publications - 40
Citations - 2482
Cleo L. Bishop is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Senescence & Human genetics. The author has an hindex of 17, co-authored 37 publications receiving 1397 citations. Previous affiliations of Cleo L. Bishop include Imperial College London & University College London.
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Journal ArticleDOI
Cellular Senescence: Defining a Path Forward
Vassilis G. Gorgoulis,Peter D. Adams,Andrea Alimonti,Dorothy C. Bennett,Oliver Bischof,Cleo L. Bishop,Judith Campisi,Manuel Collado,Konstantinos Evangelou,Gerardo Ferbeyre,Jesús Gil,Eiji Hara,Valery Krizhanovsky,Diana Jurk,Andrea B. Maier,Masashi Narita,Laura J. Niedernhofer,João F. Passos,Paul D. Robbins,Clemens A. Schmitt,John M. Sedivy,Konstantinos Vougas,Thomas von Zglinicki,Daohong Zhou,Manuel Serrano,Marco Demaria +25 more
TL;DR: A consensus from the International Cell Senescence Association (ICSA) is presented, defining and discussing key cellular and molecular features of senescence and offering recommendations on how to use them as biomarkers.
Journal ArticleDOI
Multiple microRNAs rescue from Ras-induced senescence by inhibiting p21(Waf1/Cip1).
Viola Borgdorff,M E Lleonart,Cleo L. Bishop,Delphine Fessart,Ann-Marie H. Bergin,Marita G. Overhoff,David H. Beach +6 more
TL;DR: The results establish an important role for the cell cycle inhibitor p21Waf1/Cip1 in growth control of HMECs and extend the repertoire of miRNAs that modulate the activity of this tumour suppressor.
Journal ArticleDOI
A whole genome screen for HIV restriction factors
Li Liu,Nidia M M Oliveira,Kelly M. Cheney,Corinna Pade,Hanna Dreja,Ann Marie H. Bergin,Viola Borgdorff,David H. Beach,Cleo L. Bishop,Matthias T. Dittmar,Áine McKnight +10 more
TL;DR: It is proposed that the PAF1c establishes an anti-viral state to prevent infection by incoming retroviruses, a previously unrecognised mechanism of restriction that could have implications for invasion of cells by any pathogen.
Journal ArticleDOI
A multidimensional systems biology analysis of cellular senescence in aging and disease
Roberto A. Avelar,Javier Gómez Ortega,Javier Gómez Ortega,Robi Tacutu,Robi Tacutu,Eleanor J. Tyler,Dominic Bennett,Paolo Binetti,Arie Budovsky,Kasit Chatsirisupachai,Emily Johnson,Alex Murray,Samuel Shields,Daniela Tejada-Martinez,Daniela Tejada-Martinez,Daniel Thornton,Vadim E. Fraifeld,Cleo L. Bishop,João Pedro de Magalhães +18 more
TL;DR: This work develops CellAge, a manually curated database of 279 human genes driving cellular senescence, and performs various integrative analyses that reveal new insights and gene regulators of cellularsenescence.