R
Roy N. Platt
Researcher at Texas Biomedical Research Institute
Publications - 49
Citations - 2419
Roy N. Platt is an academic researcher from Texas Biomedical Research Institute. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 18, co-authored 44 publications receiving 1520 citations. Previous affiliations of Roy N. Platt include Mississippi State University & Texas Tech University.
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Journal ArticleDOI
Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs
Richard E. Green,Edward L. Braun,Joel Armstrong,Dent Earl,Ngan Nguyen,Glenn Hickey,Michael W. Vandewege,John St. John,Salvador Capella-Gutierrez,Todd A. Castoe,Todd A. Castoe,Colin Kern,Matthew K. Fujita,Juan C. Opazo,Jerzy Jurka,Kenji K. Kojima,Juan Caballero,Robert Hubley,Arian F.A. Smit,Roy N. Platt,Christine A. Lavoie,Meganathan P. Ramakodi,John W. Finger,Alexander Suh,Alexander Suh,Sally R. Isberg,Lee G. Miles,Amanda Y. Chong,Weerachai Jaratlerdsiri,Jaime Gongora,Chris Moran,Andrés Iriarte,John E. McCormack,Shane C. Burgess,Scott V. Edwards,Eric Lyons,Christina L. Williams,Matthew Breen,Jason T. Howard,Cathy R. Gresham,Daniel G. Peterson,Juergen Schmitz,David D. Pollock,David Haussler,David Haussler,Eric W. Triplett,Guojie Zhang,Naoki Irie,Erich D. Jarvis,Christopher A. Brochu,Carl J. Schmidt,Fiona M. McCarthy,Brant C. Faircloth,Brant C. Faircloth,Federico G. Hoffmann,Travis C. Glenn,Toni Gabaldón,Toni Gabaldón,Benedict Paten,David A. Ray,David A. Ray +60 more
TL;DR: An exceptionally slow rate of genome evolution within crocodilians at all levels is observed, consistent with a single underlying cause of a reduced rate of evolutionary change rather than intrinsic differences in base repair machinery.
Journal ArticleDOI
Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice.
Fatai S. Oladunni,Jun-Gyu Park,Paula A. Pino,Olga Gonzalez,Anwari Akhter,Anna Allué-Guardia,Angélica Olmo-Fontánez,Angélica Olmo-Fontánez,Shalini Gautam,Andreu Garcia-Vilanova,Chengjin Ye,Kevin Chiem,Kevin Chiem,Colwyn A. Headley,Varun Dwivedi,Laura M. Parodi,Kendra J. Alfson,Hilary M. Staples,Alyssa Schami,Alyssa Schami,Juan Ignacio García,Alison Whigham,Roy N. Platt,Michal Gazi,Jesse Martinez,Colin Chuba,Stephanie Earley,Oscar H. Rodriguez,Stephanie Davis Mdaki,Katrina N. Kavelish,Renee Escalona,Cory R. A. Hallam,Corbett Christie,Jean L. Patterson,Tim J. Anderson,Ricardo Carrion,Edward J. Dick,Shannan Hall-Ursone,Larry S. Schlesinger,Xavier Alvarez,Deepak Kaushal,Luis D. Giavedoni,Joanne Turner,Luis Martinez-Sobrido,Jordi B. Torrelles +44 more
TL;DR: Transgenic mice expressing human angiotensin-converting enzyme 2 by the human cytokeratin 18 promoter represent a susceptible rodent model and represent a suitable animal model for the study of viral pathogenesis and for identification and characterization of vaccines and antivirals for SARS-CoV-2 infection and associated severe COVID-19 disease.
Journal ArticleDOI
Draft genome sequence of the Tibetan antelope
Ri Li Ge,Qingle Cai,Yong Yi Shen,Yong Yi Shen,A. San,Lan Ma,Yong Zhang,Xin Yi,Yan Chen,Lingfeng Yang,Ying Huang,Rongjun He,Yuanyuan Hui,Meirong Hao,Yue Li,Bo Wang,Xiaohua Ou,Jiaohui Xu,Yongfen Zhang,Kui Wu,Chunyu Geng,Wei-Ping Zhou,Tai-Cheng Zhou,David M. Irwin,David M. Irwin,Yingzhong Yang,Liu Ying,Haihua Bao,Jaebum Kim,Jaebum Kim,Denis M. Larkin,Jian Ma,Harris A. Lewin,Jinchuan Xing,Roy N. Platt,David A. Ray,Loretta Auvil,Boris Capitanu,Xiufeng Zhang,Guojie Zhang,Robert W. Murphy,Robert W. Murphy,Jun Wang,Jun Wang,Jun Wang,Ya-Ping Zhang,Jian Wang +46 more
TL;DR: The genome of the Tibetan antelope shows signals of adaptive evolution and gene-family expansion in genes associated with energy metabolism and oxygen transmission and common genetic mechanisms might have been utilized to enable high-altitude adaptation.
Journal ArticleDOI
Evolution and Diversity of Transposable Elements in Vertebrate Genomes.
TL;DR: The current understanding of vertebrate TE diversity and evolution is reviewed and the current bottleneck in genome analyses lies in the proper annotation of TEs and examples where superficial analyses led to misleading conclusions about genome evolution are provided.
Journal ArticleDOI
Mammalian transposable elements and their impacts on genome evolution.
TL;DR: The current understanding of TE content in mammal genomes is summarized and it is found that, with a few exceptions, most fall within a predictable range of observations.