C
Craig M. Bielski
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 32
Citations - 6593
Craig M. Bielski is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Cancer & Carcinogenesis. The author has an hindex of 15, co-authored 28 publications receiving 4044 citations. Previous affiliations of Craig M. Bielski include Cornell University & Broad Institute.
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Journal ArticleDOI
Next-generation characterization of the Cancer Cell Line Encyclopedia
Mahmoud Ghandi,Franklin W. Huang,Franklin W. Huang,Franklin W. Huang,Judit Jané-Valbuena,Judit Jané-Valbuena,Gregory V. Kryukov,Christopher Lo,E. Robert McDonald,Jordi Barretina,Ellen Gelfand,Craig M. Bielski,Haoxin Li,Haoxin Li,Kevin Hu,Alexander Y. Andreev-Drakhlin,Jaegil Kim,Julian M. Hess,Brian J. Haas,François Aguet,Barbara A. Weir,Michael V. Rothberg,Brenton R. Paolella,Michael S. Lawrence,Rehan Akbani,Yiling Lu,Hong L. Tiv,Prafulla C. Gokhale,Antoine de Weck,Ali Amin Mansour,Coyin Oh,Juliann Shih,Kevin Hadi,Yanay Rosen,Jonathan Bistline,Kavitha Venkatesan,Anupama Reddy,Dmitriy Sonkin,Dmitriy Sonkin,Manway Liu,Joseph Lehar,Joshua M. Korn,Dale Porter,Michael D. Jones,Javad Golji,Giordano Caponigro,Jordan E. Taylor,Caitlin M. Dunning,Amanda L. Creech,Allison Warren,James M. McFarland,Mahdi Zamanighomi,Audrey Kauffmann,Nicolas Stransky,Marcin Imielinski,Yosef E. Maruvka,Yosef E. Maruvka,Andrew D. Cherniack,Andrew D. Cherniack,Aviad Tsherniak,Francisca Vazquez,Jacob D. Jaffe,Andrew A. Lane,David M. Weinstock,Cory M. Johannessen,Michael Morrissey,Frank Stegmeier,Robert Schlegel,William C. Hahn,William C. Hahn,Gad Getz,Gordon B. Mills,Jesse S. Boehm,Todd R. Golub,Todd R. Golub,Todd R. Golub,Levi A. Garraway,Levi A. Garraway,William R. Sellers,William R. Sellers +79 more
TL;DR: The original Cancer Cell Line Encyclopedia is expanded with deeper characterization of over 1,000 cell lines, including genomic, transcriptomic, and proteomic data, and integration with drug-sensitivity and gene-dependency data, which reveals potential targets for cancer drugs and associated biomarkers.
Journal ArticleDOI
Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
Jose U. Scher,Andrew Sczesnak,Andrew Sczesnak,Randy S. Longman,Randy S. Longman,Nicola Segata,Nicola Segata,Carles Ubeda,Carles Ubeda,Craig M. Bielski,Tim Rostron,Vincenzo Cerundolo,Eric G. Pamer,Steven B. Abramson,Curtis Huttenhower,Dan R. Littman +15 more
TL;DR: The presence of Prevotella copri is identified as strongly correlated with disease in new-onset untreated rheumatoid arthritis (NORA) patients and uniquePrevotella genes that correlate with disease are identified.
Journal ArticleDOI
The long tail of oncogenic drivers in prostate cancer
Joshua Armenia,Stephanie A. Wankowicz,Stephanie A. Wankowicz,David Liu,David Liu,Jianjiong Gao,Ritika Kundra,Ed Reznik,Walid K. Chatila,Debyani Chakravarty,G. Celine Han,G. Celine Han,Ilsa Coleman,Bruce Montgomery,Colin C. Pritchard,Colm Morrissey,Christopher E. Barbieri,Himisha Beltran,Himisha Beltran,Andrea Sboner,Zafeiris Zafeiriou,Susana Miranda,Craig M. Bielski,Alexander V Penson,Charlotte Tolonen,Franklin W. Huang,Franklin W. Huang,Dan R. Robinson,Yi-Mi Wu,Robert J. Lonigro,Levi A. Garraway,Levi A. Garraway,Francesca Demichelis,Philip W. Kantoff,Mary-Ellen Taplin,Wassim Abida,Barry S. Taylor,Howard I. Scher,Peter S. Nelson,Peter S. Nelson,Johann S. de Bono,Mark A. Rubin,Mark A. Rubin,Charles L. Sawyers,Arul M. Chinnaiyan,Nikolaus Schultz,Eliezer M. Van Allen,Eliezer M. Van Allen +47 more
TL;DR: A new class of E26 transformation-specific (ETS)-fusion-negative tumors defined by mutations in epigenetic regulators, as well as alterations in pathways not previously implicated in prostate cancer, such as the spliceosome pathway are identified.
Journal ArticleDOI
The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers.
Pedram Razavi,Matthew T. Chang,Guotai Xu,Chaitanya Bandlamudi,Dara S. Ross,Neil Vasan,Yanyan Cai,Craig M. Bielski,Mark T.A. Donoghue,Philip Jonsson,Alexander V Penson,Ronglai Shen,Fresia Pareja,Ritika Kundra,Sumit Middha,Michael L. Cheng,Ahmet Zehir,Cyriac Kandoth,Ruchi Patel,Kety Huberman,Lillian M. Smyth,Komal Jhaveri,Shanu Modi,Tiffany A. Traina,Chau T. Dang,Wen Zhang,Britta Weigelt,Bob T. Li,Marc Ladanyi,David M. Hyman,Nikolaus Schultz,Mark E. Robson,Clifford A. Hudis,Edi Brogi,Agnes Viale,Larry Norton,Maura N. Dickler,Michael F. Berger,Christine A. Iacobuzio-Donahue,Sarat Chandarlapaty,Maurizio Scaltriti,Jorge S. Reis-Filho,David B. Solit,Barry S. Taylor,José Baselga +44 more
TL;DR: An increased number of alterations in genes involved in the mitogen-activated protein kinase (MAPK) pathway and in the estrogen receptor transcriptional machinery were identified in breast cancers exposed to hormonal therapy and associated with a shorter duration of response to subsequent hormonal therapies.
Journal ArticleDOI
Genome doubling shapes the evolution and prognosis of advanced cancers
Craig M. Bielski,Ahmet Zehir,Alexander V Penson,Mark T.A. Donoghue,Walid K. Chatila,Joshua Armenia,Matthew T. Chang,Matthew T. Chang,Alison M. Schram,Philip Jonsson,Chaitanya Bandlamudi,Pedram Razavi,Gopa Iyer,Mark E. Robson,Zsofia K. Stadler,Nikolaus Schultz,José Baselga,David B. Solit,David M. Hyman,David M. Hyman,Michael F. Berger,Barry S. Taylor +21 more
TL;DR: WGD predicted for increased morbidity across cancer types, including KRAS-mutant colorectal cancers and estrogen receptor-positive breast cancers, independently of established clinical prognostic factors.