Daji Luo

TL;DR: By using a ribozyme to co-transcriptionally cleave nascent RNA, it is demonstrated that a free RNA end coupled with a G/C-skewed sequence is necessary and sufficient to induce R-loop, providing a topological solution for RNA invasion into duplex DNA and suggesting an order for R- loop initiation and elongation in an opposite direction to that previously proposed.

TL;DR: A large-scale RBP ChIP-seq analysis reveals widespread RBP presence in active chromatin regions in the human genome, and proposes that various RBPs may enhance network interaction through harnessing regulatory RNAs to control transcription.

TL;DR: It is demonstrated that fish and mammals have evolved different strategies for neuroendocrine control of reproduction, suggesting that the kiss/kissr systems play nonessential roles for reproduction in certain nonmammalian vertebrates.

TL;DR: Results point to a novel role for EYS in maintaining the morphological structure of F-actin and in protein transport, loss of this function might be the trigger for the resultant cellular events that ultimately lead to photoreceptor death.

TL;DR: The results establish TALENs as a robust tool to engineer large genomic deletions and knockout of ncRNA genes, thus opening up new avenues in the application of TALens to study the genome in vivo.