D
Dan Lindholm
Researcher at Minerva Foundation Institute for Medical Research
Publications - 266
Citations - 25963
Dan Lindholm is an academic researcher from Minerva Foundation Institute for Medical Research. The author has contributed to research in topics: Nerve growth factor & Neurotrophic factors. The author has an hindex of 70, co-authored 235 publications receiving 23924 citations. Previous affiliations of Dan Lindholm include University of Melbourne & Max Planck Society.
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Rat retinal ganglion cells upregulate the pro-apoptotic BH3-only protein Bim after optic nerve transection
TL;DR: The results suggest that Bim is involved in injury-induced retinal ganglion cell death and indicate that the increase in Bim and Bax expression promote cell death of axotomized retinalganglion cells whereas the elevation in Bcl-2 in retina may contribute to the control of the extent of apoptosis after the optic nerve transection.
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Low Levels of Nerve Growth Factor in Cerebrospinal Fluid of Children With Rett Syndrome
TL;DR: Nerve growth factor levels were significantly lower in the cerebrospinal fluid of the patients with Rett syndrome than in control patients, suggesting that lack of nerve growth factor may be involved in the pathogenesis of this disease or reflect the underlying brain damage present.
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Transforming growth factor beta expression in reactive spinal cord microglia and meningeal inflammatory cells during experimental allergic neuritis
TL;DR: The data indicate that TGF‐β1 and ‐β3 are involved in regulating the glial response in EAN and that activated microglial cells might control their own activity state by expressing TGF-β1.
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Developmental Regulation of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) and Its Receptor 1 in Rat Brain: Function of PACAP as a Neurotrophic Factora
TL;DR: Experimental results that indicate the presence of PACAP and its receptor in the developing nervous system, together with the observed neuropeptide activity on various populations of neurons, support the view that PACAP exhibits important neurotrophic activities comparable to those of the classical neurotrophic factors.
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Differential expression of bcl-w and bcl-x messenger RNA in the developing and adult rat nervous system
TL;DR: The present results suggest that bcl-w may play an important role in the mature nervous system.