D
Dan Lindholm
Researcher at Minerva Foundation Institute for Medical Research
Publications - 266
Citations - 25963
Dan Lindholm is an academic researcher from Minerva Foundation Institute for Medical Research. The author has contributed to research in topics: Nerve growth factor & Neurotrophic factors. The author has an hindex of 70, co-authored 235 publications receiving 23924 citations. Previous affiliations of Dan Lindholm include University of Melbourne & Max Planck Society.
Papers
More filters
Journal ArticleDOI
Time to Clinical Benefit of Dapagliflozin in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction
Muthiah Vaduganathan,Brian Claggett,Pardeep S. Jhund,W. De Boer,Adrian F. Hernandez,Silvio E. Inzucchi,Mikhail Kosiborod,Carolyn S.P. Lam,Felipe Martinez,Akshay S. Desai,Sheila M. Hegde,Dan Lindholm,Magnus Petersson,Anna Maria Langkilde,John J.V. McMurray,Scott D. Solomon +15 more
TL;DR: In the DELIVER trial, dapagliflozin led to early and sustained reductions in clinical events in patients with HF with mildly reduced or preserved ejection fraction with statistically significant reductions observed within 2 weeks of treatment initiation.
Journal ArticleDOI
ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments
TL;DR: In this paper , the unique role of endoplasmic reticulum (ER) stress in AD pathogenesis was analyzed and a thorough elucidation of ER stress machinery in AD pathology may help to open up new therapeutic avenues in the management of this devastating condition.
Journal ArticleDOI
Prostaglandin D2 Receptor DP1 Antibodies Predict Vaccine-induced and Spontaneous Narcolepsy Type 1: Large-scale Study of Antibody Profiling
Helle Sadam,Arno Pihlak,Anri Kivil,Susan Pihelgas,Mariliis Jaago,Priit Adler,Jaak Vilo,Olli Vapalahti,Toomas Neuman,Dan Lindholm,Markku Partinen,Antti Vaheri,Kaia Palm +12 more
TL;DR: It is proposed that DP1 is a novel molecular target of autoimmune response and presents a potential diagnostic biomarker for NT1, which is involved in the regulation of non-rapid eye movement (NREM) sleep and thus alterations in its functions could contribute to the disturbed sleep regulation in NT1.
Journal Article
PDGF regulates the actin cytoskeleton through hnRNP-K-mediated activation of
Kohji Nagano,Beat Bornhauser,Gayathri Warnasuriya,Alan Entwistle,Rainer Cramer,Dan Lindholm,Soren Naaby-Hansen +6 more
TL;DR: The results show that activation of MIR and the resulting removal of diphosphorylated MRLC are essential for PDGF to instigate and maintain control over the actin–myosin‐based contractile system in Swiss 3T3 fibroblasts.
Journal ArticleDOI
Dexamethasone regulates expression of BRUCE/Apollon and the proliferation of neural progenitor cells
Maria Sippel,Raili Rajala,Laura Korhonen,Beat Bornhauser,Beat Bornhauser,Anna-Leena Sokka,Mikihiko Naito,Dan Lindholm +7 more
TL;DR: MINT‐7148555: Nrdp1 physically interacts with Usp8 by anti bait co‐immunoprecipitation byAnti bait co-immunofiltration by uniprotkb-based approaches.