D
Dan Lindholm
Researcher at Minerva Foundation Institute for Medical Research
Publications - 266
Citations - 25963
Dan Lindholm is an academic researcher from Minerva Foundation Institute for Medical Research. The author has contributed to research in topics: Nerve growth factor & Neurotrophic factors. The author has an hindex of 70, co-authored 235 publications receiving 23924 citations. Previous affiliations of Dan Lindholm include University of Melbourne & Max Planck Society.
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Book ChapterDOI
Neurotrophins as Mediators of Neuronal Plasticity
Andrea Blöchl,Benedikt Berninger,Maria da Penha Berzaghi,Eero Castrén,Dan Lindholm,Hans Thoenen +5 more
TL;DR: The hypothesis that the neurotrophins may stabilize and/or rearrange specific synapses in an activity-dependent manner is supported by recent observations that long-term potentiation is strongly impaired in hippocampal slices of homo- and heterozygote BDNF knock-out mice.
Journal ArticleDOI
Amyotrophic lateral sclerosis: evidence for intact hepatocyte growth factor/met signalling axis
Michael A. Kern,Michael A. Kern,Michael Friese,Eva Grundstrom,Laura Korhonen,Anders Wallin,Sten-Magnus Aquilonius,Håkan Askmark,Peter Schirmacher,Dan Lindholm +9 more
TL;DR: The data demonstrate that ALS does not show a lack of the trophic signalling axis, HGF/MET, suggesting that the signalling system itself is not affected, and a moderate increase in HGF-secretion may represent a compensatory effect.
Journal ArticleDOI
Machine learning for improved detection of myocardial infarction in patients presenting with chest pain in the emergency department
Dan Lindholm,Martin J. Holzmann +1 more
TL;DR: Machine Learning For Improved Detection of Myocardial Infarction In Patients Presenting With Chest Pain In The Emergency Department shows promising results in terms of improved detection of myocardial infarction.
Journal ArticleDOI
PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice.
Taavi Vanaveski,Svetlana M. Molchanova,Dan Duc Pham,Dan Duc Pham,Annika Schäfer,Annika Schäfer,Ceren Pajanoja,Ceren Pajanoja,Jane Narvik,Vignesh Srinivasan,Vignesh Srinivasan,Mari Urb,Maria Koivisto,Maria Koivisto,Eero Vasar,Tõnis Timmusk,Rimante Minkeviciene,Ove Eriksson,Maciej Lalowski,Maciej Lalowski,Tomi Taira,Laura Korhonen,Vootele Voikar,Dan Lindholm,Dan Lindholm +24 more
TL;DR: In this article, the authors observed that the protein levels of γ-aminobutyric acid (GABA) type A receptor-α2 subunit (GABARα2) were increased in hippocampus and brain cortex in transgenic (Tg) mice overexpressing PGC-1α in neurons.
Journal ArticleDOI
Ticagrelor versus clopidogrel in patients with non-st-elevation acute coronary syndrome : results from the PLATO trial
Dan Lindholm,Christoph Varenhorst,Christopher P. Cannon,Robert A. Harrington,Anders Himmelmann,Juan Maya,Steen Husted,Hugo A. Katus,Philippe Gabriel Steg,Robert F. Storey,Lars Wallentin,Stefan James +11 more
TL;DR: Ticagrelor versus clopidogrel in patients with non-st-elevation acute coronary syndrome : results from the PLATO trial.