D
Dan Lindholm
Researcher at Minerva Foundation Institute for Medical Research
Publications - 266
Citations - 25963
Dan Lindholm is an academic researcher from Minerva Foundation Institute for Medical Research. The author has contributed to research in topics: Nerve growth factor & Neurotrophic factors. The author has an hindex of 70, co-authored 235 publications receiving 23924 citations. Previous affiliations of Dan Lindholm include University of Melbourne & Max Planck Society.
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X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia.
Xiaoyang Wang,Xiaoyang Wang,Changlian Zhu,Changlian Zhu,Xinhua Wang,Xinhua Wang,Henrik Hagberg,Henrik Hagberg,Laura Korhonen,Mats Sandberg,Dan Lindholm,Klas Blomgren,Klas Blomgren +12 more
TL;DR: Findings provide the first evidence that increased XIAP levels protect the neonatal brain against HI, and XIAP was colocalized with XAF-1, Smac, and HtrA2 in injured neurons after hypoxia-ischemia.
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Biomarkers in Relation to the Effects of Ticagrelor in Comparison With Clopidogrel in Non–ST-Elevation Acute Coronary Syndrome Patients Managed With or Without In-Hospital Revascularization A Substudy From the Prospective Randomized Platelet Inhibition and Patient Outcomes (PLATO) Trial
Lars Wallentin,Dan Lindholm,Agneta Siegbahn,Lisa Wernroth,Richard C. Becker,Christopher P. Cannon,Jan H. Cornel,Anders Himmelmann,Evangelos Giannitsis,Robert A. Harrington,Claes Held,Steen Husted,Hugo A. Katus,Kenneth W. Mahaffey,Ph. Gabriel Steg,Robert F. Storey,Stefan James +16 more
TL;DR: High-sensitivity troponin T, N-terminal pro-brain natriuretic peptide, and growth differentiation factor-15 are predictors of cardiovascular death, myocardial infarction, and stroke in patients with NSTE-ACS managed noninvasively, and NT-proBNP and GDF-15 also in those managed invasively.
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Differential Effects of MK-801 on Brain-Derived Neurotrophic Factor mRNA Levels in Different Regions of the Rat Brain
TL;DR: The observations made with MK-801 demonstrate that depending on the neuronal connections and the transmitter systems involved, a given compound can elicit either a decrease or an increase in BDNF mRNA levels.
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Neurotrophic and neuroprotective effects of pituitary adenylate cyclase-activating polypeptide (pACAP) on mesencephalic dopaminergic neurons
TL;DR: The results show that PACAP has a neurotrophic action on dopaminergic neurons and partially protects them against 6‐OHDA induced neurotoxicity.
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bcl-2 Messenger RNA is localized in neurons of the developing and adult rat brain
TL;DR: It is found that low levels of bcl-2 messenger RNA are widely distributed in the adult and developing rat brain and the hypothesis that induction of bCl-2 Messenger RNA expression might be part of the survival-promoting action of neurotrophic factors is tested.