D
Dan Lindholm
Researcher at Minerva Foundation Institute for Medical Research
Publications - 266
Citations - 25963
Dan Lindholm is an academic researcher from Minerva Foundation Institute for Medical Research. The author has contributed to research in topics: Nerve growth factor & Neurotrophic factors. The author has an hindex of 70, co-authored 235 publications receiving 23924 citations. Previous affiliations of Dan Lindholm include University of Melbourne & Max Planck Society.
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Journal ArticleDOI
Efficacy and Safety of Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction According to Age: The DELIVER Trial
Alexander Peikert,Felipe Martinez,Muthiah Vaduganathan,Brian Claggett,Ian J. Kulac,Akshay S. Desai,Pardeep S. Jhund,W. De Boer,David L. DeMets,Adrian F. Hernandez,Silvio E. Inzucchi,Mikhail Kosiborod,Carolyn S.P. Lam,Tsvetana Katova,Béla Merkely,Orly Vardeny,Ulrica Wilderäng,Dan Lindholm,Magnus Petersson,Anna Maria Langkilde,John J.V. McMurray,Scott D. Solomon +21 more
TL;DR: In patients with heart failure and mildly reduced or preserved ejection fraction enrolled in DELIVER, dapagliflozin reduced the combined risk of cardiovascular death or worsening heart failure events across the spectrum of age, with a consistent safety profile.
Book ChapterDOI
In Vitro and in Vivo Methods for Evaluating Actions of Cytokines on Nerve Growth Factor Production in Central Nervous System
TL;DR: The methods used to study the influence of Interleukin 1 (IL-1) and transforming growth factor β 1 (TGF-β) on nerve growth factor (NGF) production in cultured brain cells and in vivo are discussed.
Journal ArticleDOI
Identification of Antibodies against HAI-1 and Integrin α6β4 as Immunohistochemical Markers of Human Villous Cytotrophoblast:
Outi Hallikas,Johanna Aaltonen,Harriet von Koskull,L.-A. Lindberg,Leena Valmu,Nisse Kalkkinen,Torsten Wahlström,Hiroaki Kataoka,Leif C. Andersson,Dan Lindholm,J. Schröder +10 more
TL;DR: Monoclonal antibody MG2 was specific to villous cytotrophoblast across gestation, and recognizes hepatocyte growth factor activator inhibitor type 1 and MAb MD10 recognizes human integrin α6β4.
Journal ArticleDOI
Neural network and "Ganglion" formations in vitro : a video microscopy and scanning electron microscopy study on adult cultured spiral ganglion cells.
Marja Boström,Malin Anderson,Dan Lindholm,Kyoung-Ho Park,Annelies Schrott-Fischer,Kristian Pfaller,Rudolf Glueckert,Helge Rask-Andersen +7 more
TL;DR: This method of culturing and expanding spiral ganglion neurons in vitro may be useful in further studies of cell transplantation models aiming to restore the injured inner ear.
Journal ArticleDOI
The E3 ubiquitin ligase inducible degrader of the LDL receptor/myosin light chain interacting protein in health and disease.
TL;DR: IDOL is emerging as an important determinant of lipid and energy metabolism in metabolic disease as well as in Alzheimer's disease, and the potential for therapeutic targeting of IDOL may be beneficial in treating these conditions.