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Daniel Schwenk

Researcher at Schiller International University

Publications -  9
Citations -  527

Daniel Schwenk is an academic researcher from Schiller International University. The author has contributed to research in topics: Polyketide synthase & Phanerochaete. The author has an hindex of 8, co-authored 9 publications receiving 456 citations. Previous affiliations of Daniel Schwenk include University of Jena.

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Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete chrysosporium provide insight into selective ligninolysis

Elena Fernández-Fueyo, +65 more
TL;DR: In this paper, a comparative genome analysis of C. subvermispora and P. chrysosporium was conducted to investigate the basis for selective ligninolysis.
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Homologous NRPS-like Gene Clusters Mediate Redundant Small-Molecule Biosynthesis in Aspergillus flavus

TL;DR: The use of comparative metabolomics is demonstrated for the analysis of knock-out, overexpression, and knock-down strains to identify metabolites derived from two nonribosomal peptide synthetase (NRPS) gene clusters in the aflatoxin-producing ascomycete Aspergillus flavus, a crop contaminant and opportunistic pathogen that causes aspergillosis in immunocompromised humans.
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Involutin is an Fe3+ reductant secreted by the ectomycorrhizal fungus Paxillus involutus during Fenton-based decomposition of organic matter.

TL;DR: The results show that the mechanism for the reduction of Fe3+ and the generation of hydroxyl radicals via Fenton chemistry by ectomycorrhizal fungi during organic matter decomposition is similar to that employed by the evolutionarily related brown rot saprotrophs during wood decay.
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A gene cluster responsible for biosynthesis of phomenoic acid in the plant pathogenic fungus, Leptosphaeria maculans.

TL;DR: Reduced expression of an adjacent gene encoding the transcriptional regulator C6TF led to reduced expression of genes for PKS2, P450, a cytochrome P450 monoxygenase, YogA, an alcohol dehydrogenase/quinone reductase, RTA1, a lipid transport exporter superfamily member and MFS, a Major Facilitator Superfamily transporter, as well as a marked reduction in phomenoic acid production.
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Biochemical and genetic basis of orsellinic acid biosynthesis and prenylation in a stereaceous basidiomycete.

TL;DR: In vitro characterization showed that BYPB activity depends on bivalent cations and that it uses orsellinic acid as acceptor substrate for the transfer of a prenyl group, which supports the emerging notion that fungi secure individual metabolic steps or entire pathways by redundant enzymes.