D
Daria Salyakina
Researcher at Boston Children's Hospital
Publications - 69
Citations - 5048
Daria Salyakina is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 26, co-authored 60 publications receiving 4580 citations. Previous affiliations of Daria Salyakina include John P. Hussman Institute for Human Genomics & University of Miami.
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Journal ArticleDOI
Common genetic variants on 5p14.1 associate with autism spectrum disorders
Kai Wang,Haitao Zhang,Deqiong Ma,Maja Bucan,Joseph T. Glessner,Brett S. Abrahams,Daria Salyakina,Marcin Imielinski,Jonathan P. Bradfield,Patrick M. A. Sleiman,Cecilia E. Kim,Cuiping Hou,Edward C. Frackelton,Rosetta M. Chiavacci,Nagahide Takahashi,Takeshi Sakurai,Eric F. Rappaport,Clara Lajonchere,Jeffrey Munson,Annette Estes,Olena Korvatska,Joseph Piven,Lisa I. Sonnenblick,Ana I. Alvarez Retuerto,Edward I. Herman,Hongmei Dong,Ted Hutman,Marian Sigman,Sally J Ozonoff,Ami Klin,Thomas Owley,John A. Sweeney,Camille W. Brune,Rita M. Cantor,Raphael Bernier,John R. Gilbert,Michael L. Cuccaro,William M. McMahon,Judith Miller,Matthew W. State,Thomas H. Wassink,Hilary Coon,Susan E. Levy,Robert T. Schultz,John I. Nurnberger,Jonathan L. Haines,James S. Sutcliffe,Edwin H. Cook,Nancy J. Minshew,Joseph D. Buxbaum,Geraldine Dawson,Struan F.A. Grant,Daniel H. Geschwind,Margaret A. Pericak-Vance,Gerard D. Schellenberg,Hakon Hakonarson +55 more
TL;DR: The results implicate neuronal cell-adhesion molecules in the pathogenesis of ASDs, and represent, to the authors' knowledge, the first demonstration of genome-wide significant association of common variants with susceptibility to ASDs.
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Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment
Elisabeth B. Binder,Daria Salyakina,Peter Lichtner,G. M. Wochnik,Marcus Ising,Benno Pütz,Sergi Papiol,S. R. Seaman,Susanne Lucae,Martin A. Kohli,Thomas Nickel,Heike E. Künzel,B. Fuchs,M. Majer,Andrea Pfennig,N. Kern,J. Brunner,Sieglinde Modell,Thomas C. Baghai,Tobias Deiml,Peter Zill,Brigitta Bondy,Rainer Rupprecht,Thomas Messer,Oliver Köhnlein,Heike Dabitz,Tanja Brückl,N. Müller,Hildegard Pfister,Roselind Lieb,Jakob C. Mueller,Elin Lõhmussaar,Tim M. Strom,Thomas Bettecken,Thomas Meitinger,Manfred Uhr,Theo Rein,Florian Holsboer,Bertram Müller-Myhsok +38 more
TL;DR: It is proposed that the FKBP5 variant–dependent alterations in HPA-axis regulation could be related to the faster response to antidepressant drug treatment and the increased recurrence of depressive episodes observed in this subgroup of depressed individuals.
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Polymorphisms in the drug transporter Gene ABCB1 predict antidepressant treatment response in depression
Manfred Uhr,Alina Tontsch,Christian Namendorf,Stephan Ripke,Susanne Lucae,Marcus Ising,T. Dose,Martin Ebinger,Marcus C. Rosenhagen,Martin A. Kohli,Stefan Kloiber,Daria Salyakina,Thomas Bettecken,Michael Specht,Benno Pütz,Elisabeth B. Binder,Bertram Müller-Myhsok,Florian Holsboer +17 more
TL;DR: It is reported that polymorphisms in the ABCB1 gene predict the response to antidepressant treatment in those depressed patients receiving drugs that have been identified as substrates ofABCB1 using abcb1ab double-knockout mice.
Journal ArticleDOI
Polymorphisms of the Glucocorticoid Receptor Gene and Major Depression
Elisabeth F.C. van Rossum,Elisabeth B. Binder,M. Majer,Jan W. Koper,Marcus Ising,Sieglinde Modell,Daria Salyakina,Steven W. J. Lamberts,Florian Holsboer +8 more
TL;DR: Findings support the notion that variants of the GR gene might play a role in the pathophysiology of a major depression and can contribute to the variability of antidepressant response.
Journal ArticleDOI
P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
Susanne Lucae,Daria Salyakina,Nicholas Barden,Mario Harvey,Bernard Gagné,Michel Labbé,Elisabeth B. Binder,Manfred Uhr,Marcelo Paez-Pereda,Inge Sillaber,Marcus Ising,Tanja Brückl,Roselind Lieb,Florian Holsboer,Bertram Müller-Myhsok +14 more
TL;DR: A non-synonymous coding SNP in the P2RX7 gene (rs2230912), previously found to be associated with bipolar disorder, was significantly associated with MDD, suggesting that the observed P2 RX7 polymorphism might play a causal role in the development of depression.