D
Dirk A. E. Dobbelaere
Researcher at University of Bern
Publications - 68
Citations - 3563
Dirk A. E. Dobbelaere is an academic researcher from University of Bern. The author has contributed to research in topics: Theileria parva & Theileria. The author has an hindex of 34, co-authored 68 publications receiving 3374 citations.
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Journal ArticleDOI
The top 100 questions of importance to the future of global agriculture
Jules Pretty,William J. Sutherland,Jacqueline Anne Ashby,Jill S. Auburn,David C. Baulcombe,Michael J. Bell,Jeffrey Bentley,Sam Bickersteth,Katrina Brown,Jacob Burke,Hugh Campbell,Kevin Chen,Eve Crowley,I. R. Crute,Dirk A. E. Dobbelaere,Gareth Edwards-Jones,F. R. Funes-Monzote,H. Charles J. Godfray,Michel Griffon,Phrek Gypmantisiri,Lawrence Haddad,Siosiua Halavatau,H. R. Herren,Mark Holderness,Anne-Marie Izac,Monty Jones,Parviz Koohafkan,Rattan Lal,Tim Lang,Jeffrey A. McNeely,Alexander Mueller,Nicholas Nisbett,Andrew Noble,Prabhu Pingali,Yvonne M. Pinto,Rudy Rabbinge,N. H. Ravindranath,Agnes C. Rola,Niels Röling,Colin Sage,William H. Settle,J M Sha,Luo Shiming,Tony Simons,Pete Smith,Kenneth Strzepeck,Harry Swaine,Eugene Terry,Thomas P. Tomich,Camilla Toulmin,Eduardo Trigo,Stephen Twomlow,Jan Kees Vis,Jeremy D. Wilson,Sarah Pilgrim +54 more
TL;DR: The UK Government's Foresight Global Food and Farming Futures project as mentioned in this paper aims to improve dialogue and understanding between agricultural research and policy by identifying the 100 most important questions for global agriculture.
Journal ArticleDOI
Genome of the host-cell transforming parasite Theileria annulata compared with T. parva.
Arnab Pain,Hubert Renauld,Matthew Berriman,Lee Murphy,Corin Yeats,William Weir,Arnaud Kerhornou,Martin Aslett,Richard P. Bishop,Christiane Bouchier,Madeleine Cochet,Richard M.R. Coulson,Ann Cronin,Etienne P. de Villiers,Audrey Fraser,Nigel Fosker,Malcolm J. Gardner,Arlette Goble,Sam Griffiths-Jones,David Harris,Frank Katzer,Natasha Larke,Angela Lord,Pascal Mäser,Sue McKellar,P. Mooney,Fraser R. Morton,Vishvanath Nene,Susan O'Neil,Claire Price,Michael A. Quail,Ester Rabbinowitsch,Neil D. Rawlings,Simon Rutter,David L. Saunders,Kathy Seeger,Trushar Shah,R. Squares,S. Squares,Adrian Tivey,Alan R. Walker,John Woodward,Dirk A. E. Dobbelaere,Gordon Langsley,Marie Adele Rajandream,Declan J. McKeever,Brian Shiels,Andrew Tait,Bart Barrell,Neil Hall +49 more
TL;DR: The genome of T. annulata is sequenced and the analysis reveals unequally expanded gene families and species-specific genes, and divergent families of putative secreted polypeptides that may reduce immune recognition.
Journal ArticleDOI
Transformation of Leukocytes by Theileria parva and T. annulata
TL;DR: The presence of the parasite in the host-cell cytoplasm modulates the state of activation of a number of signal transduction pathways, including nuclear factor-kappa B, which appear to be essential for the survival of Theileria-transformed T cells.
Journal ArticleDOI
A Metabolic Enzyme as a Primary Virulence Factor of Mycoplasma mycoides subsp. mycoides Small Colony
Paola Pilo,Edy M. Vilei,Ernst Peterhans,Laetitia Bonvin-Klotz,Michael Hubert Stoffel,Dirk A. E. Dobbelaere,Joachim Frey +6 more
TL;DR: A novel primary virulence determinant is identified in Mycoplasma mycoides subsp.
Journal ArticleDOI
Hijacking of host cell IKK signalosomes by the transforming parasite Theileria
Volker Heussler,Sven Rottenberg,Rebekka Schwab,Peter Küenzi,Paula C. Fernandez,Susan McKellar,Brian Shiels,Zhijian J. Chen,Kim Orth,David Wallach,Dirk A. E. Dobbelaere +10 more
TL;DR: This work found that survival of Theileria-transformed leukocytes depends strictly on constitutive nuclear factor kappa B activity and found that this was mediated by recruitment of the multisubunit IκB kinase into large, activated foci on the parasite surface.