D
Dulanjalee Kariyawasam
Researcher at French Institute of Health and Medical Research
Publications - 31
Citations - 525
Dulanjalee Kariyawasam is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 10, co-authored 19 publications receiving 321 citations. Previous affiliations of Dulanjalee Kariyawasam include Harvard University & Boston Children's Hospital.
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Journal ArticleDOI
Association of Prenatal and Postnatal Exposure to Lopinavir-Ritonavir and Adrenal Dysfunction Among Uninfected Infants of HIV-Infected Mothers
Albane Simon,Josiane Warszawski,Dulanjalee Kariyawasam,Jérôme Le Chenadec,Valérie Benhammou,Paul Czernichow,Frantz Foissac,Kathleen Laborde,Jean-Marc Tréluyer,Ghislaine Firtion,Inès Layouni,Martine Munzer,Françoise Bavoux,Michel Polak,Stéphane Blanche +14 more
TL;DR: Postnatal treatment with a lopinavir-ritonavir-based regimen, compared with a zidovudine- based regimen, was associated with transient adrenal dysfunction among newborn children of HIV-1-infected mothers exposed in utero to lop Scandinavia.
Journal ArticleDOI
TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology.
Athanasia Stoupa,Frédéric Adam,Dulanjalee Kariyawasam,Catherine Strassel,Sanjay Gawade,Gabor Szinnai,Gabor Szinnai,Alexandre Kauskot,Dominique Lasne,Dominique Lasne,Carsten Janke,Carsten Janke,Kathiresan Natarajan,Kathiresan Natarajan,Alain Schmitt,Christine Bole-Feysot,Patrick Nitschke,Juliane Léger,Fabienne Jabot-Hanin,Frédéric Tores,Anita Luise Michel,Arnold Munnich,Arnold Munnich,Claude Besmond,Raphael Scharfmann,François Lanza,Delphine Borgel,Delphine Borgel,Michel Polak,Aurore Carré +29 more
TL;DR: The genetic causes of congenital hypothyroidism due to thyroid dysgenesis (TD) are identified and three novel TUBB1 gene mutations that co‐segregated with TD in three distinct families leading to 1.1% of TubB1 mutations in TD study cohort are identified.
Journal ArticleDOI
Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance
Latif Rachdi,Dulanjalee Kariyawasam,Virginie Aiello,Yann Herault,Nathalie Janel,Jean-Maurice Delabar,Michel Polak,Raphael Scharfmann +7 more
TL;DR: In this article, the authors used mice overexpressing Dyrk1A under the control of its own regulatory sequences (mBACTgDyrk 1A) to increase functional β cell mass and insulin sensitivity.
Journal ArticleDOI
Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation
Emanuele Pignatti,Emanuele Pignatti,Sining Leng,Sining Leng,Yixing Yuchi,Yixing Yuchi,Kleiton Silva Borges,Kleiton Silva Borges,Nick A. Guagliardo,Manasvi S. Shah,Manasvi S. Shah,Gerard Ruiz-Babot,Gerard Ruiz-Babot,Dulanjalee Kariyawasam,Dulanjalee Kariyawasam,Makoto Mark Taketo,Ji Miao,Ji Miao,Paula Q. Barrett,Diana L. Carlone,Diana L. Carlone,David T. Breault,David T. Breault +22 more
TL;DR: It is found that β-catenin drives adrenal hyperplasia through both proliferation-dependent and -independent mechanisms, and is further exacerbated by trophic factor stimulation leading to organomegaly.
Journal ArticleDOI
Mutations in BOREALIN cause thyroid dysgenesis.
Aurore Carré,Athanasia Stoupa,Dulanjalee Kariyawasam,Manelle Gueriouz,Cyrille Ramond,Taylor M Monus,Juliane Léger,Sébastien Gaujoux,Frédéric Sebag,Nicolas Glaser,Delphine Zenaty,Patrick Nitschke,Christine Bole-Feysot,Laurence Hubert,Stanislas Lyonnet,Stanislas Lyonnet,Raphael Scharfmann,Arnold Munnich,Arnold Munnich,Claude Besmond,William R. Taylor,Michel Polak +21 more
TL;DR: The novel missense mutations p.S148F, p.R114Q and p.L177W in the BOREALIN gene in TD‐affected families were identified and opened new avenues in the genetics of TD in humans.