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Elizabeth A. Veal
Researcher at Newcastle University
Publications - 36
Citations - 4106
Elizabeth A. Veal is an academic researcher from Newcastle University. The author has contributed to research in topics: Thioredoxin peroxidase activity & Peroxiredoxin. The author has an hindex of 25, co-authored 35 publications receiving 3577 citations. Previous affiliations of Elizabeth A. Veal include University of Liverpool & University of Newcastle.
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Journal ArticleDOI
Hydrogen Peroxide Sensing and Signaling
TL;DR: The molecular mechanisms by which hydrogen peroxide is sensed and the increasing evidence that antioxidant enzymes play multiple, key roles as sensors and regulators of signal transduction in response to hydrogen peroxy are discussed.
Journal ArticleDOI
European contribution to the study of ROS : a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Javier Egea,Isabel Fabregat,Yves Frapart,Pietro Ghezzi,Agnes Görlach,Thomas Kietzmann,Kateryna Kubaichuk,Ulla G. Knaus,Manuela G. López,Gloria Olaso-Gonzalez,Andreas Petry,Rainer Schulz,Jose Viña,Paul J Winyard,Kahina Abbas,Opeyemi S Ademowo,Catarina B. Afonso,Ioanna Andreadou,Haike Antelmann,Fernando Antunes,Mutay Aslan,Markus Bachschmid,Rui M. Barbosa,Vsevolod V. Belousov,Carsten Berndt,David A. Bernlohr,Esther Bertran,Alberto Bindoli,Serge P. Bottari,Paula M. Brito,Guia Carrara,Ana I. Casas,Afroditi Chatzi,Niki Chondrogianni,Marcus Conrad,Marcus S. Cooke,João G. Costa,Antonio Cuadrado,Pham My-Chan Dang,Barbara De Smet,Bilge Debelec-Butuner,Irundika H.K. Dias,Joe Dan Dunn,Amanda J. Edson,Mariam El Assar,Jamel El-Benna,Péter Ferdinandy,Ana Sofia Fernandes,Kari E. Fladmark,Ulrich Förstermann,Rashid Giniatullin,Zoltán Giricz,Anikó Görbe,Helen L Griffiths,Helen L Griffiths,Vaclav Hampl,Alina Hanf,Jan Herget,Pablo Hernansanz-Agustín,Melanie Hillion,Jingjing Huang,Serap Ilikay,Pidder Jansen-Dürr,Vincent Jaquet,Jaap A. Joles,Balaraman Kalyanaraman,Danylo Kaminskyy,Mahsa Karbaschi,Marina Kleanthous,Lars-Oliver Klotz,Bato Korac,Kemal Sami Korkmaz,Rafal Koziel,Damir Kračun,Karl-Heinz Krause,Vladimír Křen,Thomas Krieg,João Laranjinha,Antigone Lazou,Huige Li,Antonio Martínez-Ruiz,Reiko Matsui,Gethin J. McBean,Stuart P. Meredith,Joris Messens,Verónica Miguel,Yuliya Mikhed,Irina Milisav,Lidija Milkovic,Antonio Miranda-Vizuete,Miloš Mojović,María Monsalve,Pierre-Alexis Mouthuy,John F. Mulvey,Thomas Münzel,Vladimir R. Muzykantov,Isabel T.N. Nguyen,Matthias Oelze,Nuno G. Oliveira,Carlos M. Palmeira,Nikoletta Papaevgeniou,Aleksandra Pavićević,Brandán Pedre,Fabienne Peyrot,Marios Phylactides,Gratiela Gradisteanu Pircalabioru,Andrew R. Pitt,Henrik E. Poulsen,Ignacio Prieto,Maria Pia Rigobello,Natalia Robledinos-Antón,Leocadio Rodríguez-Mañas,Anabela P. Rolo,Francis Rousset,Tatjana Ruskovska,Nuno Saraiva,Shlomo Sasson,Katrin Schröder,Khrystyna Semen,Tamara Seredenina,Anastasia Shakirzyanova,Geoffrey L. Smith,Thierry Soldati,Bebiana C. Sousa,Corinne M. Spickett,Ana Stancic,Marie José Stasia,Holger Steinbrenner,Višnja Stepanić,Sebastian Steven,Kostas Tokatlidis,Erkan Tuncay,Belma Turan,Fulvio Ursini,Jan Vacek,Olga Vajnerova,Kateřina Valentová,Frank Van Breusegem,Lokman Varisli,Elizabeth A. Veal,A. Süha Yalçın,Olha Yelisyeyeva,Neven Žarković,Martina Zatloukalová,Jacek Zielonka,Rhian M. Touyz,Andreas Papapetropoulos,Tilman Grune,Santiago Lamas,Harald H.H.W. Schmidt,Fabio Di Lisa,Andreas Daiber +151 more
TL;DR: The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks and EU-ROS represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine.
Journal ArticleDOI
A 2-Cys Peroxiredoxin Regulates Peroxide-Induced Oxidation and Activation of a Stress-Activated MAP Kinase
Elizabeth A. Veal,Victoria J. Findlay,Alison M. Day,Stephanie M. Bozonet,Jennifer M. Evans,Janet Quinn,Brian A. Morgan +6 more
TL;DR: It is revealed that Tpx1, the single 2-Cys Prx in Schizosaccharomyces pombe, is required for the peroxide-induced activation of the p38/JNK homolog, Sty1, which provides new insight into the response of SAPKs to diverse stimuli by revealing a mechanism for SAPK activation specifically by oxidative stress.
Journal ArticleDOI
Hydrogen Peroxide as a Signaling Molecule
Elizabeth A. Veal,Alison M. Day +1 more
TL;DR: Some of the mechanisms by which hydrogen peroxide is sensed and utilized as a signaling molecule to regulate diverse biological processes are discussed.
Journal ArticleDOI
Inactivation of a Peroxiredoxin by Hydrogen Peroxide Is Critical for Thioredoxin-Mediated Repair of Oxidized Proteins and Cell Survival
Alison M. Day,Jonathon D. Brown,Sarah R. Taylor,Jonathan D. Rand,Brian A. Morgan,Elizabeth A. Veal +5 more
TL;DR: It is shown that, in cells treated with hydrogen peroxide, the Prx Tpx1 is a major substrate for thioredoxin in the fission yeast Schizosaccharomyces pombe and, as such, competitively inhibits thiOREDoxin-mediated reduction of other oxidized proteins.