E
Elizabeth Levandowsky
Researcher at Life Technologies
Publications - 5
Citations - 199
Elizabeth Levandowsky is an academic researcher from Life Technologies. The author has contributed to research in topics: Population & Genome. The author has an hindex of 4, co-authored 5 publications receiving 188 citations.
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Journal ArticleDOI
Population Genetic Inference from Personal Genome Data: Impact of Ancestry and Admixture on Human Genomic Variation
Jeffrey M. Kidd,Simon Gravel,Jake K. Byrnes,Andrés Moreno-Estrada,Shaila Musharoff,Katarzyna Bryc,Jeremiah D. Degenhardt,Abra Brisbin,Vrunda Sheth,Rong Chen,Stephen F. McLaughlin,Heather E. Peckham,Larsson Omberg,Christina A. Bormann Chung,Sarah Stanley,Kevin A. Pearlstein,Elizabeth Levandowsky,Suehelay Acevedo-Acevedo,Adam Auton,Alon Keinan,Victor Acuña-Alonzo,Rodrigo Barquera-Lozano,Samuel Canizales-Quinteros,Celeste Eng,Esteban G. Burchard,Archie Russell,Andrew R. Reynolds,Andrew G. Clark,Martin G. Reese,Stephen E. Lincoln,Atul J. Butte,Francisco M. De La Vega,Francisco M. De La Vega,Carlos Bustamante +33 more
TL;DR: A systematic analysis of 50 human genomes from 11 diverse global populations sequenced at high coverage identifies subtle variations across populations in the proportion of neutral versus deleterious variation and finds that genome-wide statistics vary in admixed populations even once ancestry proportions have been factored in.
Journal ArticleDOI
Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing.
Sebastiaan van Heesch,Wigard P. Kloosterman,Nico Lansu,Frans-Paul Ruzius,Elizabeth Levandowsky,Clarence Lee,Shiguo Zhou,Steve Goldstein,David C. Schwartz,Timothy T. Harkins,Victor Guryev,Edwin Cuppen +11 more
TL;DR: It is concluded that applying combinations of mate-pair libraries with insert sizes that match the distributions of repetitive elements improves contig scaffolding and can contribute to the finishing of draft genomes.
Journal ArticleDOI
Low-Pass Genome-Wide Sequencing and Variant Inference Using Identity-by-Descent in an Isolated Human Population
Alexander Gusev,Minita Shah,Eimear E. Kenny,Arthi Ramachandran,Jennifer K. Lowe,Jennifer K. Lowe,Jennifer K. Lowe,J. Salit,J. Salit,Clarence Lee,Elizabeth Levandowsky,T. N. Weaver,Q. C. Doan,Heather E. Peckham,Stephen F. McLaughlin,Michael R. Lyons,Vrunda Sheth,Markus Stoffel,F. M. De La Vega,Jeffrey M. Friedman,Jan L. Breslow,Itsik Pe'er +21 more
TL;DR: This study presents whole-genome analysis of a homogenous isolate population with emphasis on optimal rare variant inference and identifies long regions with haplotypes co-inherited between pairs of individuals and methodology to leverage such shared genetic content for imputation.
Journal ArticleDOI
The Possibility of De Novo Assembly of the Genome and Population Genomics of the Mangrove Rivulus, Kryptolebias marmoratus
Joanna L. Kelley,Muh-Ching Yee,Clarence Lee,Elizabeth Levandowsky,Minita Shah,Timothy T. Harkins,Ryan L. Earley,Carlos Bustamante +7 more
TL;DR: The attributes of Kryptolebias marmoratus are described, one of two known self-fertilizing hermaphroditic vertebrates that make this fish an attractive genetic system and a model for understanding the genomics of adaptation and as a new model organism for behavioral genetics and evolutionary genetics research.
Posted Content
Low-pass Genomewide Sequencing and Variant Imputation Using Identity-by-descent in an Isolated Human Population
Alexander Gusev,Minita Shah,Eimear E. Kenny,Arthi Ramachandran,Jennifer K. Lowe,J. Salit,Clarence Lee,Elizabeth Levandowsky,T. N. Weaver,Q. C. Doan,Heather E. Peckham,Stephen F. McLaughlin,Vrunda Sheth,Markus Stoffel,F. M. De La Vega,Jeffrey M. Friedman,Jan L. Breslow,Itsik Pe'er +17 more
TL;DR: This study presents the first whole-genome analysis of a homogenous isolate population with emphasis on rare variant inference and reports identification of long regions with haplotypes co-inherited between pairs of individuals and methodology to leverage such shared genetic content for imputation.