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Ellen Kirstine Lyhne
Researcher at Technical University of Denmark
Publications - 6
Citations - 483
Ellen Kirstine Lyhne is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Genome & Whole genome sequencing. The author has an hindex of 5, co-authored 6 publications receiving 353 citations.
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Journal ArticleDOI
Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri
Tammi Camilla Vesth,Jane L. Nybo,Sebastian Theobald,Jens Christian Frisvad,Thomas Ostenfeld Larsen,Kristian Fog Nielsen,Jakob Blæsbjerg Hoof,Julian Brandl,Asaf Salamov,Robert Riley,Robert Riley,John M. Gladden,John M. Gladden,Pallavi A. Phatale,Pallavi A. Phatale,Morten Thrane Nielsen,Ellen Kirstine Lyhne,Martin Engelhard Kogle,Kimchi Strasser,Erin McDonnell,Kerrie Barry,Alicia Clum,Cindy Chen,Kurt LaButti,Sajeet Haridas,Matt Nolan,Laura Sandor,Alan Kuo,Anna Lipzen,Matthieu Hainaut,Matthieu Hainaut,Elodie Drula,Elodie Drula,Adrian Tsang,Jon K. Magnuson,Jon K. Magnuson,Bernard Henrissat,Bernard Henrissat,Bernard Henrissat,Ad Wiebenga,Blake A. Simmons,Blake A. Simmons,Miia R. Mäkelä,Miia R. Mäkelä,Ronald P. de Vries,Igor V. Grigoriev,Igor V. Grigoriev,Uffe Hasbro Mortensen,Scott E. Baker,Scott E. Baker,Mikael Rørdam Andersen +50 more
TL;DR: Experimental and computational analyses showed that both secondary metabolism and regulation are key factors that are significant in the delineation of Aspergillus species.
Journal ArticleDOI
Linking secondary metabolites to gene clusters through genome sequencing of six diverse Aspergillus species
Inge Kjærbølling,Tammi Camilla Vesth,Jens Christian Frisvad,Jane L. Nybo,Sebastian Theobald,Alan Kuo,Paul Bowyer,Yudai Matsuda,Stephen J. Mondo,Ellen Kirstine Lyhne,Martin Engelhard Kogle,Alicia Clum,Anna Lipzen,Asaf Salamov,Chew Yee Ngan,Chris Daum,Jennifer Chiniquy,Kerrie Barry,Kurt LaButti,Sajeet Haridas,Blake A. Simmons,Jon K. Magnuson,Jon K. Magnuson,Uffe Hasbro Mortensen,Thomas Ostenfeld Larsen,Igor V. Grigoriev,Igor V. Grigoriev,Scott E. Baker,Scott E. Baker,Mikael Rørdam Andersen +29 more
TL;DR: Six whole-genome sequences that represent unexplored branches of the Aspergillus genus are presented, showing the large diversity found in the As pergilli genus; highlights the potential for discovery of beneficial or harmful SMs; and supports reports of A. novofumigatus pathogenicity.
Journal ArticleDOI
A comparative genomics study of 23 Aspergillus species from section Flavi
Inge Kjærbølling,Tammi Camilla Vesth,Jens Christian Frisvad,Jane L. Nybo,Sebastian Theobald,Sara Kildgaard,Thomas Isbrandt Petersen,Alan Kuo,Atsushi Sato,Ellen Kirstine Lyhne,Martin Engelhard Kogle,Ad Wiebenga,Roland S. Kun,Ronnie J. M. Lubbers,Miia R. Mäkelä,Kerrie Barry,Mansi Chovatia,Alicia Clum,Chris Daum,Sajeet Haridas,Guifen He,Kurt LaButti,Anna Lipzen,Stephen J. Mondo,Jasmyn Pangilinan,Robert Riley,Asaf Salamov,Blake A. Simmons,Jon K. Magnuson,Bernard Henrissat,Uffe Hasbro Mortensen,Thomas Ostenfeld Larsen,Ronald P. de Vries,Igor V. Grigoriev,Igor V. Grigoriev,Masayuki Machida,Scott E. Baker,Scott E. Baker,Mikael Rørdam Andersen +38 more
TL;DR: Analysis of the genomes of 23 Flavi species shows high genetic diversity and potential for synthesis of over 13,700 CAZymes and 1600 secondary metabolites and identification of secondary metabolites, highlights the genetic and metabolic diversity within section Flavi.
Journal ArticleDOI
Secondary metabolite and mycotoxin production by the Rhizopus microsporus group.
Jennifer Jennessen,Kristian Fog Nielsen,Jos Houbraken,Ellen Kirstine Lyhne,Johan Schnürer,Jens Christian Frisvad,Robert A. Samson +6 more
TL;DR: Liquid chromatography, combined with photodiode array detection and high-resolution mass spectrometric techniques, was used to identify secondary metabolites and growth on maize, brown rice, and Pharma agar gave both the highest amounts and the maximum diversity of rhizoxins and rhizonins.
Journal ArticleDOI
Four psychrotolerant species with high chemical diversity consistently producing cycloaspeptide A, Penicillium jamesonlandense sp. nov., Penicillium ribium sp. nov., Penicillium soppii and Penicillium lanosum.
Jens Christian Frisvad,Thomas Ostenfeld Larsen,Petur Weihe Dalsgaard,Keith A. Seifert,Gerry Louis-Seize,Ellen Kirstine Lyhne,Bruce B. Jarvis,James C. Fettinger,David P. Overy +8 more
TL;DR: Cycloaspeptide A is reported here for the first time from the two novel Penicillium species and two known psychrotolerant species with high chemical diversity, Penicllium soppii and Penicilium lanosum.