J
Jane L. Nybo
Researcher at Technical University of Denmark
Publications - 5
Citations - 467
Jane L. Nybo is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Genome & Comparative genomics. The author has an hindex of 5, co-authored 5 publications receiving 313 citations.
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Journal ArticleDOI
Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri
Tammi Camilla Vesth,Jane L. Nybo,Sebastian Theobald,Jens Christian Frisvad,Thomas Ostenfeld Larsen,Kristian Fog Nielsen,Jakob Blæsbjerg Hoof,Julian Brandl,Asaf Salamov,Robert Riley,Robert Riley,John M. Gladden,John M. Gladden,Pallavi A. Phatale,Pallavi A. Phatale,Morten Thrane Nielsen,Ellen Kirstine Lyhne,Martin Engelhard Kogle,Kimchi Strasser,Erin McDonnell,Kerrie Barry,Alicia Clum,Cindy Chen,Kurt LaButti,Sajeet Haridas,Matt Nolan,Laura Sandor,Alan Kuo,Anna Lipzen,Matthieu Hainaut,Matthieu Hainaut,Elodie Drula,Elodie Drula,Adrian Tsang,Jon K. Magnuson,Jon K. Magnuson,Bernard Henrissat,Bernard Henrissat,Bernard Henrissat,Ad Wiebenga,Blake A. Simmons,Blake A. Simmons,Miia R. Mäkelä,Miia R. Mäkelä,Ronald P. de Vries,Igor V. Grigoriev,Igor V. Grigoriev,Uffe Hasbro Mortensen,Scott E. Baker,Scott E. Baker,Mikael Rørdam Andersen +50 more
TL;DR: Experimental and computational analyses showed that both secondary metabolism and regulation are key factors that are significant in the delineation of Aspergillus species.
Journal ArticleDOI
Linking secondary metabolites to gene clusters through genome sequencing of six diverse Aspergillus species
Inge Kjærbølling,Tammi Camilla Vesth,Jens Christian Frisvad,Jane L. Nybo,Sebastian Theobald,Alan Kuo,Paul Bowyer,Yudai Matsuda,Stephen J. Mondo,Ellen Kirstine Lyhne,Martin Engelhard Kogle,Alicia Clum,Anna Lipzen,Asaf Salamov,Chew Yee Ngan,Chris Daum,Jennifer Chiniquy,Kerrie Barry,Kurt LaButti,Sajeet Haridas,Blake A. Simmons,Jon K. Magnuson,Jon K. Magnuson,Uffe Hasbro Mortensen,Thomas Ostenfeld Larsen,Igor V. Grigoriev,Igor V. Grigoriev,Scott E. Baker,Scott E. Baker,Mikael Rørdam Andersen +29 more
TL;DR: Six whole-genome sequences that represent unexplored branches of the Aspergillus genus are presented, showing the large diversity found in the As pergilli genus; highlights the potential for discovery of beneficial or harmful SMs; and supports reports of A. novofumigatus pathogenicity.
Journal ArticleDOI
A comparative genomics study of 23 Aspergillus species from section Flavi
Inge Kjærbølling,Tammi Camilla Vesth,Jens Christian Frisvad,Jane L. Nybo,Sebastian Theobald,Sara Kildgaard,Thomas Isbrandt Petersen,Alan Kuo,Atsushi Sato,Ellen Kirstine Lyhne,Martin Engelhard Kogle,Ad Wiebenga,Roland S. Kun,Ronnie J. M. Lubbers,Miia R. Mäkelä,Kerrie Barry,Mansi Chovatia,Alicia Clum,Chris Daum,Sajeet Haridas,Guifen He,Kurt LaButti,Anna Lipzen,Stephen J. Mondo,Jasmyn Pangilinan,Robert Riley,Asaf Salamov,Blake A. Simmons,Jon K. Magnuson,Bernard Henrissat,Uffe Hasbro Mortensen,Thomas Ostenfeld Larsen,Ronald P. de Vries,Igor V. Grigoriev,Igor V. Grigoriev,Masayuki Machida,Scott E. Baker,Scott E. Baker,Mikael Rørdam Andersen +38 more
TL;DR: Analysis of the genomes of 23 Flavi species shows high genetic diversity and potential for synthesis of over 13,700 CAZymes and 1600 secondary metabolites and identification of secondary metabolites, highlights the genetic and metabolic diversity within section Flavi.
Journal ArticleDOI
The gold-standard genome of Aspergillus niger NRRL 3 enables a detailed view of the diversity of sugar catabolism in fungi
Maria Victoria Aguilar-Pontes,Julian Brandl,E. McDonnell,K. Strasser,T.T.M. Nguyen,Robert Riley,Stephen J. Mondo,Asaf Salamov,Jane L. Nybo,Tammi Camilla Vesth,Igor V. Grigoriev,Mikael Rørdam Andersen,Adrian Tsang,R.P. de Vries +13 more
TL;DR: This study demonstrates how one gold-standard genome can improve functional prediction across closely related species to be able to identify key enzymes, reactions and pathways with the focus on primary carbon metabolism.
Journal ArticleDOI
An Integrated Metabolomic and Genomic Mining Workflow To Uncover the Biosynthetic Potential of Bacteria.
Maria Maansson,Nikolaj Grønnegaard Vynne,Andreas Klitgaard,Jane L. Nybo,Jette Melchiorsen,Don D. Nguyen,Laura M. Sanchez,Nadine Ziemert,Pieter C. Dorrestein,Mikael Rørdam Andersen,Lone Gram +10 more
TL;DR: An integrated approach to evaluate the biosynthetic richness in bacteria and mine the associated chemical diversity is presented, showing the usefulness of this combined approach in a group of marine Gram-negative bacteria closely related to Pseudoalteromonas luteoviolacea, which is a species known to produce a broad spectrum of chemicals.