E
Evan J. Anderson
Researcher at Emory University
Publications - 283
Citations - 19308
Evan J. Anderson is an academic researcher from Emory University. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 40, co-authored 217 publications receiving 11203 citations. Previous affiliations of Evan J. Anderson include Children's Memorial Hospital & Northwestern University.
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Journal ArticleDOI
An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
Lisa A. Jackson,Evan J. Anderson,Nadine Rouphael,Paul C. Roberts,Mamodikoe Makhene,Rhea N. Coler,Michele Paine McCullough,James D. Chappell,Mark R. Denison,Laura J. Stevens,Andrea J. Pruijssers,Adrian B. McDermott,Britta Flach,Nicole A. Doria-Rose,Kizzmekia S. Corbett,Kaitlyn M. Morabito,Sijy O’Dell,Stephen D. Schmidt,Phillip A. Swanson,Marcelino Padilla,John R. Mascola,Kathleen M. Neuzil,Hamilton Bennett,Wellington Sun,Etza Peters,Mat Makowski,Jim Albert,Kaitlyn Cross,Wendy Buchanan,Rhonda Pikaart-Tautges,Julie E. Ledgerwood,Barney S. Graham,John H. Beigel +32 more
TL;DR: The mRNA-1273 vaccine induced anti-SARS-CoV-2 immune responses in all participants, and no trial-limiting safety concerns were identified, which support further development of this vaccine.
Journal ArticleDOI
Community-acquired pneumonia requiring hospitalization among U.S. adults
Seema Jain,Derek J. Williams,Sandra R. Arnold,Krow Ampofo,Anna M. Bramley,Carrie Reed,Chris Stockmann,Evan J. Anderson,Carlos G. Grijalva,Wesley H. Self,Yuwei Zhu,Anami Patel,Weston Hymas,James D. Chappell,Robert A. Kaufman,J. Herman Kan,David Dansie,Noel Lenny,David R. Hillyard,Lia M. Haynes,Min Z. Levine,Stephen Lindstrom,Jonas M. Winchell,Jacqueline M. Katz,Dean D. Erdman,Eileen Schneider,Lauri A. Hicks,Richard G. Wunderink,Kathryn M. Edwards,Andrew T. Pavia,Jonathan A. McCullers,Lyn Finelli +31 more
TL;DR: The incidence of community-acquired pneumonia requiring hospitalization was highest among the oldest adults and despite current diagnostic tests, no pathogen was detected in the majority of patients.
Journal ArticleDOI
Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 - COVID-NET, 14 States, March 1-30, 2020.
Shikha Garg,Shikha Garg,Lindsay Kim,Michael Whitaker,Alissa O’Halloran,Charisse N Cummings,Rachel Holstein,Mila M. Prill,Shua J Chai,Pam Daily Kirley,Nisha B Alden,Breanna Kawasaki,Kimberly Yousey-Hindes,Linda M. Niccolai,Evan J. Anderson,Evan J. Anderson,Kyle P Openo,Andrew Weigel,Maya Monroe,Patricia Ryan,Justin Henderson,Sue Kim,Kathy Como-Sabetti,Ruth Lynfield,Daniel M. Sosin,Salina Torres,Alison Muse,Nancy M. Bennett,Laurie M Billing,Melissa Sutton,Nicole West,William Schaffner,H. Keipp Talbot,Clarissa Aquino,Andrea George,Alicia P Budd,Lynnette Brammer,Gayle E Langley,Aron J. Hall,Alicia M. Fry +39 more
TL;DR: It is suggested that older adults have elevated rates of COVID-19-associated hospitalization and the majority of persons hospitalized with CO VID-19 have underlying medical conditions, which underscore the importance of preventive measures to protect older adults and persons with underlyingmedical conditions, as well as the general public.
Journal ArticleDOI
Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults.
Evan J. Anderson,Nadine Rouphael,Alicia T. Widge,Lisa A. Jackson,Paul C. Roberts,Mamodikoe Makhene,James D. Chappell,Mark R. Denison,Laura J. Stevens,Andrea J. Pruijssers,Adrian B. McDermott,Britta Flach,Bob C. Lin,Nicole A. Doria-Rose,Sijy O'Dell,Stephen D. Schmidt,Kizzmekia S. Corbett,Phillip A. Swanson,Marcelino Padilla,Kathy M. Neuzil,Hamilton Bennett,Brett A. Leav,Mat Makowski,Jim Albert,Kaitlyn Cross,Venkata Viswanadh Edara,Katharine Floyd,Mehul S. Suthar,David R. Martinez,Ralph S. Baric,Wendy Buchanan,Catherine J. Luke,Varun K Phadke,Christina A. Rostad,Julie E. Ledgerwood,Barney S. Graham,John H. Beigel +36 more
TL;DR: The phase 1, dose-escalation, open-label trial of a messenger RNA vaccine, mRNA-1273, which encodes the stabilized prefusion SARS-CoV-2 spike protein in healthy adults found it induced higher binding- and neutralizing-antibody titers than the 25-μg dose, which supports the use of the 100- μg dose in a phase 3 vaccine trial.
Journal ArticleDOI
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans.
Prabhu S. Arunachalam,Florian Wimmers,Chris Ka Pun Mok,Ranawaka A.P.M. Perera,Madeleine K D Scott,Thomas Hagan,Natalia Sigal,Yupeng Feng,Laurel Bristow,Owen Tak-Yin Tsang,Dhananjay Wagh,John A. Coller,Kathryn L. Pellegrini,Dmitri Kazmin,Ghina Alaaeddine,Wai Shing Leung,Jacky Man Chun Chan,Thomas Shiu Hong Chik,Chris Yau Chung Choi,Christopher Huerta,Michele Paine McCullough,Huibin Lv,Evan J. Anderson,Srilatha Edupuganti,Amit A. Upadhyay,Steve E. Bosinger,Steve E. Bosinger,Holden T. Maecker,Purvesh Khatri,Nadine Rouphael,Malik Peiris,Bali Pulendran +31 more
TL;DR: In the peripheral blood mononuclear cells of COVID-19 patients, the authors observed reduced expression of human leukocyte antigen class DR (HLA-DR) and proinflammatory cytokines by myeloid cells as well as impaired mammalian target of rapamycin (mTOR) signaling and interferon-α (IFN-α) production by plasmacytoid dendritic cells.