F
Fabio Benfenati
Researcher at Istituto Italiano di Tecnologia
Publications - 424
Citations - 24243
Fabio Benfenati is an academic researcher from Istituto Italiano di Tecnologia. The author has contributed to research in topics: Synapsin & Synapsin I. The author has an hindex of 77, co-authored 406 publications receiving 21422 citations. Previous affiliations of Fabio Benfenati include University of Padua & University of Modena and Reggio Emilia.
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Journal ArticleDOI
Altered Intracellular Calcium Homeostasis Underlying Enhanced Glutamatergic Transmission in Striatal-Enriched Tyrosine Phosphatase (STEP) Knockout Mice.
Federica Bosco,Pierluigi Valente,Marco Milanese,Alessandra Piccini,Mirko Messa,Mirko Messa,Giambattista Bonanno,Paul J. Lombroso,Pietro Baldelli,Fabio Benfenati,Silvia Giovedì +10 more
TL;DR: In this paper, the striatal-enriched protein tyrosine phosphatase (STEP) was found to play an important role at nerve terminals in the regulation of Ca2+ homeostasis and neurotransmitter release.
Journal ArticleDOI
Role of pericytes in blood–brain barrier preservation during ischemia through tunneling nanotubes
Francesco Pisani,Valentina Castagnola,Laura Simone,Fabrizio Loiacono,Maria Svelto,Fabio Benfenati +5 more
TL;DR: In this article , the role of tunneling nanotubes (TNTs) in the functional dialog between human brain endothelial cells and brain pericytes co-cultured with human astrocytes was analyzed.
Journal ArticleDOI
Isobaric Labeling Proteomics Allows a High-Throughput Investigation of Protein Corona Orientation
Nara Liessi,Luca Maragliano,Luca Maragliano,Valentina Castagnola,Mattia Bramini,Mattia Bramini,Fabio Benfenati,Andrea Armirotti +7 more
TL;DR: This work shows that labeling corona proteins with isobaric tags in their native conditions and analyzing the MS/MS spectra of tryptic peptides allow an easy and high-throughput assessment of the inner/outer orientation of the corresponding proteins in the original corona.
Journal ArticleDOI
Hydrogenated Graphene Improves Neuronal Network Maturation and Excitatory Transmission.
Matteo Moschetta,Jong-Young Lee,João M. M. Rodrigues,Alice Podestà,Omar Varvicchio,Jangyup Son,Jangyup Son,Yangjin Lee,Yangjin Lee,Kwanpyo Kim,Gwan Hyoung Lee,Fabio Benfenati,Mattia Bramini,Mattia Bramini,Andrea Capasso +14 more
TL;DR: In this article, the authors used hydrogenated graphene (HGr) to improve cell-to-cell communication with respect to pristine graphene in primary cortical neurons and found that the intrinsic excitability and firing properties of neurons plated onto HGr appeared unaltered, while the basic passive and active membrane properties are fully preserved.
Proceedings ArticleDOI
Nanostructured microsphere coated with living cells and tethered with low-stiffness wire: A possible solution to brain tissue reactions
Elisa Castagnola,Sara De Faveri,Alberto Ansaldo,Emma Maggiolini,Fabio Benfenati,Davide Ricci,Luciano Fadiga +6 more
TL;DR: A probe composed by an ultrathin and ultra-flexible wire as tether and a low- impedance gold sphere microelectrode as recording/stimulation site is developed and improves the microsphere performance using PEDOT-CNT composite coating and mimic the biological composition of the host tissue by coating the probe with fibroblast cells.