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Fabio Benfenati

Researcher at Istituto Italiano di Tecnologia

Publications -  424
Citations -  24243

Fabio Benfenati is an academic researcher from Istituto Italiano di Tecnologia. The author has contributed to research in topics: Synapsin & Synapsin I. The author has an hindex of 77, co-authored 406 publications receiving 21422 citations. Previous affiliations of Fabio Benfenati include University of Padua & University of Modena and Reggio Emilia.

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Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions (synaptic transmissionysynaptic plasticityysynaptic vesicle proteinsysignal transductionysynaptogenesis)

TL;DR: It is reported here that synapsin I is a downstream effector for the neurotrophin/Trk/MAP kinase cascade and may contribute to the modulation of synaptic plasticity by neurotrophins and by other signaling pathways that converge at the level of MAP kinase activation.
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Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.

TL;DR: In this article, it was shown that MAP kinase-dependent phosphorylation of synapsin I significantly reduced its ability to promote G-actin polymerization and to bundle actin filaments.
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Synaptophysin: Leading actor or walk-on role in synaptic vesicle exocytosis?

TL;DR: The main results of the studies on Syp are summarized, and it is explained why it is believed that Syp plays a major role in SV trafficking.