F
Fabio Benfenati
Researcher at Istituto Italiano di Tecnologia
Publications - 424
Citations - 24243
Fabio Benfenati is an academic researcher from Istituto Italiano di Tecnologia. The author has contributed to research in topics: Synapsin & Synapsin I. The author has an hindex of 77, co-authored 406 publications receiving 21422 citations. Previous affiliations of Fabio Benfenati include University of Padua & University of Modena and Reggio Emilia.
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APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development.
Alessandra Piccini,Enrico Castroflorio,Pierluigi Valente,Fabrizia C. Guarnieri,Davide Aprile,Caterina Michetti,Mattia Bramini,Giorgia Giansante,Bruno Pinto,Annalisa Savardi,Fabrizia Cesca,Angela Bachi,Angela Cattaneo,Jonathan D. Wren,Anna Fassio,Flavia Valtorta,Fabio Benfenati,Silvia Giovedì +17 more
TL;DR: It is shown that the previously uncharacterized protein KIAA1107, predicted by bioinformatics analysis to be involved in the SV cycle, is an AP2-interacting clathrin-endocytosis protein (APache), and the data implicate APache as an actor in the complex regulation of SV trafficking, neuronal development, and synaptic plasticity.
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Aging brain and dopamine receptors: Abnormal regulation by CCK‐8 of 3H‐spiperone labeled dopamine receptors in striatal membranes
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Effects of synaptic vesicles on actin polymerization
TL;DR: The state of association of synapsin I with synaptic vesicles, which is modulated by its state of phosphorylation, may affect actin assembly and the physico‐chemical characteristics of theaptic vesicle microenvironment.
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REST/NRSF deficiency impairs autophagy and leads to cellular senescence in neurons
Anna Rocchi,Emanuele Carminati,Emanuele Carminati,Antonio De Fusco,Jagoda Aleksandra Kowalska,Thomas Floss,Fabio Benfenati +6 more
TL;DR: In this paper, the authors show that REST deficiency causes failure of autophagy and loss of proteostasis, increased oxidative stress, and higher rate of cell death in primary mouse neurons.
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Protein phosphorylation in the nerve terminal.
Fabio Benfenati,Flavia Valtorta +1 more