F
Fabio Benfenati
Researcher at Istituto Italiano di Tecnologia
Publications - 424
Citations - 24243
Fabio Benfenati is an academic researcher from Istituto Italiano di Tecnologia. The author has contributed to research in topics: Synapsin & Synapsin I. The author has an hindex of 77, co-authored 406 publications receiving 21422 citations. Previous affiliations of Fabio Benfenati include University of Padua & University of Modena and Reggio Emilia.
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Journal ArticleDOI
Sound-Driven Synaptic Inhibition in Primary Visual Cortex
Giuliano Iurilli,Diego Ghezzi,Umberto Olcese,Glenda Lassi,Cristiano Nazzaro,Raffaella Tonini,Valter Tucci,Fabio Benfenati,Paolo Medini +8 more
TL;DR: Auditory cortex activation by salient stimuli degrades potentially distracting sensory processing in visual cortex by recruiting local, translaminar, inhibitory circuits, via cortico-cortical connections.
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Acute stress increases depolarization-evoked glutamate release in the rat prefrontal/frontal cortex: the dampening action of antidepressants.
Laura Musazzi,Marco Milanese,Pasqualina Farisello,Simona Zappettini,Daniela Tardito,V.S. Barbiero,Tiziana Bonifacino,Alessandra Mallei,Pietro Baldelli,Giorgio Racagni,Maurizio Raiteri,Fabio Benfenati,Giambattista Bonanno,Maurizio Popoli +13 more
TL;DR: Patch-clamp recordings of pyramidal neurons in the prefrontal cortex revealed that stress increased glutamatergic transmission through both pre- and postsynaptic mechanisms, and that antidepressants may normalize it by reducing release probability.
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Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc.
Giampietro Schiavo,Bernard Poulain,Ornella Rossetto,Fabio Benfenati,L. Tauc,Cesare Montecucco +5 more
TL;DR: The present findings indicate that tetanus toxin, and possibly also the botulinum neurotoxins, are metalloproteases and that they block neurotransmitter release via this protease activity.
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Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I.
Fabio Benfenati,Flavia Valtorta,James L. Rubenstein,Fred S. Gorelick,Paul Greengard,Andrew J. Czernik +5 more
TL;DR: It is demonstrated that the binding of the C-terminal region of synapsin I involves the regulatory domain of a synaptic vesicle-associated form of Ca2+/calmodulin-dependent protein kinase II, and that this form of the kinase functions both as a binding protein for synapsIn I, and as an enzyme that phosphorylates synapin I and promotes its dissociation from the vesicles.
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A polymer optoelectronic interface restores light sensitivity in blind rat retinas
Diego Ghezzi,Maria Rosa Antognazza,Rita Maccarone,Sebastiano Bellani,Sebastiano Bellani,Erica Lanzarini,Nicola Martino,Nicola Martino,Maurizio Mete,Grazia Pertile,Silvia Bisti,Guglielmo Lanzani,Guglielmo Lanzani,Fabio Benfenati +13 more
TL;DR: It is demonstrated that this bio-organic interface restored light sensitivity in explants of rat retinas with light-induced photoreceptor degeneration, suggesting that all-organic devices may play an important future role in sub-retinal prosthetic implants.