F
Fabio Benfenati
Researcher at Istituto Italiano di Tecnologia
Publications - 424
Citations - 24243
Fabio Benfenati is an academic researcher from Istituto Italiano di Tecnologia. The author has contributed to research in topics: Synapsin & Synapsin I. The author has an hindex of 77, co-authored 406 publications receiving 21422 citations. Previous affiliations of Fabio Benfenati include University of Padua & University of Modena and Reggio Emilia.
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Journal ArticleDOI
Heterogeneity of presynaptic proteins: do not forget isoforms
Luca Bragina,Giorgia Fattorini,Silvia Giovedì,Federica Bosco,Fabio Benfenati,Fabio Benfenati,Fiorenzo Conti +6 more
TL;DR: It is shown that the possibility that not all families of presynaptic proteins are expressed in all terminals must be taken into serious account and the expression of a given protein isoform in a terminal does not exclude theexpression of other isoforms of the same protein in the same terminal and in theSame vesicle.
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Computational Assessment of Different Structural Models for Claudin-5 Complexes in Blood–Brain Barrier Tight Junctions
TL;DR: By identifying the protein-protein surface at the core of TJ Cldn5 assemblies, this computational investigation provides a basis for the rational design of synthetic peptides and other molecules capable of opening paracellular pores in the BBB.
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Fluorescence approaches to the study of the actin-nucleating and bundling activities of synapsin I
Flavia Valtorta,P.E. Ceccaldi,F. Grohovaz,Evelina Chieregatti,Riccardo Fesce,Fabio Benfenati +5 more
TL;DR: It is suggested that synapsin I exerts a control on the physical characteristics of the cytoskeletal network of the nerve terminal and is consistent with the proposed role of synapin I in mediating the interaction of synaptic vesicles with actin.
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Phenotypic and genetic spectrum of ATP6V1A encephalopathy: a disorder of lysosomal homeostasis.
Renzo Guerrini,Davide Mei,Katalin Kerti-Szigeti,Sara Pepe,Mary Kay Koenig,Gretchen Von Allmen,Megan T. Cho,Kim McDonald,Janice Baker,Vikas Bhambhani,Zöe Powis,Lance H. Rodan,Rima Nabbout,Giulia Barcia,Jill A. Rosenfeld,Carlos A. Bacino,Cyril Mignot,L. H. Power,Catharine J. Harris,Dragan Marjanovic,Rikke S. Møller,Trine Bjørg Hammer,Riikka Keski Filppula,Päivi Vieira,Clara C. Hildebrandt,Stephanie Sacharow,Luca Maragliano,Fabio Benfenati,Katherine Lachlan,Andreas Benneche,Florence Petit,Jean-Madeleine de Sainte Agathe,Barbara Hallinan,Yue Si,Ingrid M. Wentzensen,Fanggeng Zou,Vinodh Narayanan,Naomichi Matsumoto,Alessandra Boncristiano,Giancarlo la Marca,Mitsuhiro Kato,Kristin Anderson,Carmen Barba,Luisa Sturiale,Domenico Garozzo,Roberto Bei,Laura Masuelli,Valerio Conti,Gaia Novarino,Anna Fassio +49 more
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The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes.
Linda Scaramuzza,Giuseppina De Rocco,Genni Desiato,Clementina Cobolli Gigli,Martina Chiacchiaretta,Filippo Mirabella,Davide Pozzi,Marco De Simone,Paola Conforti,Massimiliano Pagani,Fabio Benfenati,Fabrizia Cesca,Fabrizia Cesca,Francesco Bedogni,Nicoletta Landsberger +14 more
TL;DR: In this article, the enhancement of neuronal activity during early maturation might prevent the onset of Rett syndrome (RTT) by adding to neuronal cultures Ampakine CX546, rescues transcription of several genes, neuronal morphology, and responsiveness to stimuli.