F
Fabio Rotondo
Researcher at University of Toronto
Publications - 109
Citations - 2832
Fabio Rotondo is an academic researcher from University of Toronto. The author has contributed to research in topics: Pituitary adenoma & Pituitary tumors. The author has an hindex of 27, co-authored 108 publications receiving 2411 citations. Previous affiliations of Fabio Rotondo include St. Michael's Hospital.
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Journal Article
Endoglin (CD105): a review of its role in angiogenesis and tumor diagnosis, progression and therapy.
Farshad Nassiri,Michael D. Cusimano,Bernd W. Scheithauer,Fabio Rotondo,Alessandra Fazio,George M. Yousef,Luis V. Syro,Kalman Kovacs,Ricardo V. Lloyd +8 more
TL;DR: This review details the structure and function of endoglin, and investigates the role ofendoglin in angiogenesis and tumor diagnosis, prognosis, and therapy.
Journal ArticleDOI
Aggressive pituitary adenomas—diagnosis and emerging treatments
TL;DR: The need to develop new biomarkers to facilitate the early detection of clinically aggressive pituitary adenomas is highlighted and emerging markers that hold promise for their identification are discussed.
Journal ArticleDOI
Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations.
Leanne de Kock,Leanne de Kock,Nelly Sabbaghian,François Plourde,Archana Srivastava,Evan Weber,Dorothée Bouron-Dal Soglio,Nancy Hamel,Nancy Hamel,Joon Hyuk Choi,Sung Hye Park,Cheri Deal,Megan M. Kelsey,Megan M. Kelsey,Megan K. Dishop,Adam J. Esbenshade,John F. Kuttesch,John F. Kuttesch,Thomas S. Jacques,Arie Perry,Heinz Leichter,Philippe Maeder,Marie-Anne Brundler,Marie-Anne Brundler,Justin T. Warner,J. W. Neal,Margaret Zacharin,Márta Korbonits,Trevor Cole,Heidi Traunecker,Thomas W. McLean,Fabio Rotondo,Pierre Lepage,Steffen Albrecht,Eva Horvath,Kalman Kovacs,John R. Priest,William D. Foulkes +37 more
TL;DR: It is hypothesized that PitB is a pathognomonic feature of a germ-line DICER1 mutation and that each PitB will harbor a second somatic mutation in DICE1, a domain essential to the generation of 5p miRNAs from the 5′ arm of miRNA-precursors.
Journal ArticleDOI
Lactate Dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma
Hala Girgis,Olena Masui,Nicole M.A. White,Nicole M.A. White,Andreas Scorilas,Fabio Rotondo,Annetta Seivwright,Manal Y. Gabril,Emily Filter,Andrew H. A. Girgis,Georg A. Bjarnason,Michael A.S. Jewett,Andrew Evans,Andrew Evans,Sahar Al-Haddad,Sahar Al-Haddad,K. W. Michael Siu,George M. Yousef,George M. Yousef +18 more
TL;DR: The results indicate that LDHA up-regulation can be a predictor of poor prognosis in clear cell renal cell carcinoma, and represents a potential prognostic biomarker that can boost the accuracy of other prognostic models in patients with clear cell kidneys carcinoma.
Journal Article
Role of MGMT in tumor development, progression, diagnosis, treatment and prognosis.
TL;DR: A summary of what is known about O(6)-Methylguanine-DNA-methyltransferase, including its structure, function in its pathway, polymorphisms, expression in normal and tumoral tissue, relation to alkylating agent therapy, and possible future applications is presented.