F
Fernando J. Rossello
Researcher at Australian Regenerative Medicine Institute
Publications - 65
Citations - 2434
Fernando J. Rossello is an academic researcher from Australian Regenerative Medicine Institute. The author has contributed to research in topics: Stem cell & Biology. The author has an hindex of 21, co-authored 52 publications receiving 1545 citations. Previous affiliations of Fernando J. Rossello include Monash University & Monash Institute of Medical Research.
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Journal ArticleDOI
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes
Eliana Mariño,James L. Richards,Keiran H. McLeod,Dragana Stanley,Yu Anne Yap,Jacinta Knight,Craig R. M. McKenzie,Jan Kranich,Ana Carolina Oliveira,Fernando J. Rossello,Fernando J. Rossello,Fernando J. Rossello,Balasubramanian Krishnamurthy,Christian M. Nefzger,Christian M. Nefzger,Christian M. Nefzger,Laurence Macia,Laurence Macia,Alison N. Thorburn,Alan G. Baxter,Grant Morahan,Lee H. Wong,Jose M. Polo,Jose M. Polo,Jose M. Polo,Robert J. Moore,Trevor Lockett,Julie M. Clarke,David L. Topping,Leonard C. Harrison,Charles R. Mackay +30 more
TL;DR: Medicinal foods or metabolites might represent an effective and natural approach for countering the numerous immunological defects that contribute to T cell–dependent autoimmune diseases.
Journal ArticleDOI
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
Claudia A. Nold-Petry,Camden Lo,Ina Rudloff,Kirstin Elgass,Suzhao Li,Michael P. Gantier,Amelie S. Lotz-Havla,Søren W. Gersting,Steven X. Cho,Jason C. Lao,Andrew M. Ellisdon,Björn Rotter,Tania Azam,Niamh E. Mangan,Fernando J. Rossello,James C. Whisstock,Philip Bufler,Cecilia Garlanda,Alberto Mantovani,Charles A. Dinarello,Marcel F. Nold +20 more
TL;DR: Nold et al. as mentioned in this paper identified the receptor for IL-37 and clarified the molecular nature of the anti-inflammatory pathway induced by this cytokine, which is a member of the IL-1 family.
Journal ArticleDOI
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming
Xiaodong Liu,Christian M. Nefzger,Christian M. Nefzger,Christian M. Nefzger,Fernando J. Rossello,Fernando J. Rossello,Fernando J. Rossello,Joseph Chen,Joseph Chen,Joseph Chen,Anja S Knaupp,Anja S Knaupp,Anja S Knaupp,Jaber Firas,Jaber Firas,Jaber Firas,Ethan Ford,Jahnvi Pflueger,Jahnvi Pflueger,Jacob M. Paynter,Jacob M. Paynter,Jacob M. Paynter,Hun S. Chy,Carmel M. O’Brien,Carmel M. O’Brien,Cheng Huang,Ketan Mishra,Ketan Mishra,Ketan Mishra,Margeaux Hodgson-Garms,Margeaux Hodgson-Garms,Margeaux Hodgson-Garms,Natasha Jansz,Sarah M. Williams,Marnie E. Blewitt,Marnie E. Blewitt,Susan K. Nilsson,Susan K. Nilsson,Ralf B. Schittenhelm,Andrew L. Laslett,Andrew L. Laslett,Ryan Lister,Ryan Lister,Jose M. Polo,Jose M. Polo,Jose M. Polo +45 more
TL;DR: This work derived genetically matched naive hPSCs by direct reprogramming of fibroblasts and by primed-to-naive conversion using different naive conditions (NHSM, RSeT, 5iLAF and t2iLGöY) to demonstrate a spectrum of naive characteristics.
Journal ArticleDOI
Reprogramming roadmap reveals route to human induced trophoblast stem cells.
Xiaodong Liu,Xiaodong Liu,Xiaodong Liu,John F. Ouyang,Fernando J. Rossello,Jia Ping Tan,Jia Ping Tan,Jia Ping Tan,Kathryn C. Davidson,Kathryn C. Davidson,Kathryn C. Davidson,Daniela S. Valdes,Jan Schröder,Jan Schröder,Jan Schröder,Yu Bo Yang Sun,Yu Bo Yang Sun,Yu Bo Yang Sun,Joseph Chen,Joseph Chen,Joseph Chen,Anja S Knaupp,Anja S Knaupp,Anja S Knaupp,Guizhi Sun,Guizhi Sun,Guizhi Sun,Hun S. Chy,Hun S. Chy,Ziyi Huang,Ziyi Huang,Jahnvi Pflueger,Jahnvi Pflueger,Jaber Firas,Jaber Firas,Jaber Firas,Vincent Tano,Vincent Tano,Vincent Tano,Sam Buckberry,Sam Buckberry,Jacob M. Paynter,Jacob M. Paynter,Jacob M. Paynter,Michael R. Larcombe,Michael R. Larcombe,Michael R. Larcombe,Daniel Poppe,Daniel Poppe,Xin Yi Choo,Xin Yi Choo,Xin Yi Choo,Carmel M. O’Brien,Carmel M. O’Brien,William A. Pastor,William A. Pastor,Di Chen,Anna L. Leichter,Haroon Naeem,Pratibha Tripathi,Pratibha Tripathi,Partha Pratim Das,Partha Pratim Das,Alexandra Grubman,Alexandra Grubman,Alexandra Grubman,David R. Powell,Andrew L. Laslett,Andrew L. Laslett,Laurent David,Susan K. Nilsson,Susan K. Nilsson,Amander T. Clark,Ryan Lister,Ryan Lister,Christian M. Nefzger,Luciano G. Martelotto,Owen J. L. Rackham,Jose M. Polo,Jose M. Polo,Jose M. Polo +80 more
TL;DR: This work reconstructs molecular reprogramming trajectories of human dermal fibroblasts using single-cell transcriptomics and indicates a role for the trophectoderm-lineage-specific regulatory program during this process, and facilitates the direct reprograming of somatic cells into induced trophoblast stem cells.
Journal ArticleDOI
Transcriptional signature in microglia associated with Aβ plaque phagocytosis.
Alexandra Grubman,Alexandra Grubman,Alexandra Grubman,Xin Yi Choo,Gabriel Chew,John F. Ouyang,Guizhi Sun,Guizhi Sun,Guizhi Sun,Nathan P. Croft,Fernando J. Rossello,Fernando J. Rossello,Fernando J. Rossello,Rebecca K. Simmons,Rebecca K. Simmons,Sam Buckberry,Sam Buckberry,Dulce Vargas Landin,Dulce Vargas Landin,Jahnvi Pflueger,Jahnvi Pflueger,Teresa H. Vandekolk,Zehra C. Abay,Zehra C. Abay,Zehra C. Abay,Yichen Zhou,Xiaodong Liu,Xiaodong Liu,Xiaodong Liu,Joseph Chen,Joseph Chen,Joseph Chen,Michael R. Larcombe,Michael R. Larcombe,Michael R. Larcombe,John M. Haynes,Catriona McLean,Sarah M. Williams,Sarah M. Williams,Sarah M. Williams,Siew Yeen Chai,Trevor J Wilson,Ryan Lister,Ryan Lister,Colin W. Pouton,Anthony W. Purcell,Owen J. L. Rackham,Enrico Petretto,Jose M. Polo,Jose M. Polo,Jose M. Polo +50 more
TL;DR: The role of microglia cells in Alzheimer's disease (AD) is well recognized, however their molecular and functional diversity remain unclear as mentioned in this paper, however their role in AD is not well understood.