Françoise Lala

TL;DR: The multidomain intervention and polyunsaturated fatty acids, either alone or in combination, had no significant effects on cognitive decline over 3 years in elderly people with memory complaints.

TL;DR: The MAPT trial is presently the first largest and longest multidomain preventive trial relevant to cognitive decline in older adults with subjective memory complaints and is likely to be easily implemented within the general population.

TL;DR: The objective of the study was to assess plasma levels of Aβ42 and Aβ40 in amnestic mild cognitive impairment, nonamnestic MCI, and AD patients and to investigate relationships between peripheral and central biomarkers.

TL;DR: Multidomain interventions, targeting multiple risk factors simultaneously, could be effective dementia prevention strategies, but may be burdensome and not universally acceptable.

TL;DR: Although some studies have previously addressed the clinical impact of amyloid positron emission tomography, none has specifically addressed its selective and hierarchical implementation in relation to cerebrospinal fluid analysis in a naturalistic setting.