F
Franziska Layer
Researcher at Robert Koch Institute
Publications - 66
Citations - 2919
Franziska Layer is an academic researcher from Robert Koch Institute. The author has contributed to research in topics: Methicillin-resistant Staphylococcus aureus & Antibiotic resistance. The author has an hindex of 24, co-authored 63 publications receiving 2463 citations.
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Journal ArticleDOI
A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic
Matthew T. G. Holden,Li Yang Hsu,Li Yang Hsu,Kevin Kurt,Lucy A. Weinert,Lucy A. Weinert,Alison E. Mather,Simon R. Harris,Birgit Strommenger,Franziska Layer,Wolfgang Witte,Hermínia de Lencastre,Hermínia de Lencastre,Robert Skov,Henrik Westh,Henrik Westh,Helena Žemličková,Geoffrey W. Coombs,Angela M. Kearns,Robert Hill,Jonathan D. Edgeworth,Ian M. Gould,Vanya Gant,Jonathan Cooke,Giles Edwards,Paul R. McAdam,Kate Templeton,Angela McCann,Zhemin Zhou,Santiago Castillo-Ramírez,Edward J. Feil,Lyndsey O. Hudson,Mark C. Enright,Francois Balloux,Francois Balloux,David M. Aanensen,Brian G. Spratt,J. Ross Fitzgerald,Julian Parkhill,Mark Achtman,Stephen D. Bentley,Ulrich Nübel +41 more
TL;DR: The genetic changes associated with adaptation to the hospital environment and with increasing drug resistance over time are document, and how MRSA evolution likely has been influenced by country-specific drug use regimens are documented.
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Emergence of methicillin-resistant Staphylococcus aureus (MRSA) in different animal species
Christiane Cuny,Alexander W. Friedrich,Svetlana Kozytska,Franziska Layer,Ulrich Nübel,Knut Ohlsen,Birgit Strommenger,Birgit Walther,Lothar H. Wieler,Wolfgang Witte +9 more
TL;DR: The emergence of methicillin-resistant Staphylococcus aureus in animals such as horses, pet animals and productive livestock has raised questions of a probable human origin and in more general of host specificity of S. aUREus.
Journal ArticleDOI
Nasal Colonization of Humans with Methicillin-Resistant Staphylococcus aureus (MRSA) CC398 with and without Exposure to Pigs
Christiane Cuny,Rolf Nathaus,Franziska Layer,Birgit Strommenger,Doris Altmann,Wolfgang Witte +5 more
TL;DR: The results indicate that so far the dissemination of MRSA CC398 to non exposed humans is infrequent and probably does not reach beyond familial communities.
Journal ArticleDOI
Rare occurrence of methicillin-resistant Staphylococcus aureus CC130 with a novel mecA homologue in humans in Germany.
TL;DR: Eleven MRSA CC130 containing the mecA homologue mecALGA251 are reported from the UK and from Denmark so far from cattle and humans and as expected positive for hla, untruncated hlb, and hld.
Journal ArticleDOI
Antibiotic resistance and molecular epidemiology of Staphylococcus aureus in Nigeria
Adebayo Shittu,Adebayo Shittu,Kenneth Okon,Solayide A. Adesida,Omotayo Opemipo Oyedara,Omotayo Opemipo Oyedara,Wolfgang Witte,Birgit Strommenger,Franziska Layer,Ulrich Nübel +9 more
TL;DR: There was excellent correlation between the broth microdilution assay and detection of antibiotic resistance genes by the multiplex PCR, in the determination of S. aureus resistance to erythromycin, gentamicin, methicillin and tetracycline.