Kevin Kurt

TL;DR: The genetic changes associated with adaptation to the hospital environment and with increasing drug resistance over time are document, and how MRSA evolution likely has been influenced by country-specific drug use regimens are documented.

TL;DR: This work investigates an MRSA strain that is highly prevalent in hospitals in Central Europe and reconstructs its recent demographic history and the spatiotemporal dynamics of spread, finding extremely low diversity among European ST225 isolates, indicating that a recent population bottleneck had preceded the expansion of this clone.

TL;DR: A model for the evolution of S. aureus CC8 is proposed, involving a split into at least nine phylogenetic lineages and a subsequent series of acquisitions and losses of mobile genetic elements that carry diverse virulence and antimicrobial resistance traits.

TL;DR: It is demonstrated that phylogenetic lineages with distinct clinical properties exist within an S. aureus clonal complex, and that SNPs serve as powerful discriminatory markers, able to identify these lineages.

TL;DR: An epidemic sub-clone within CC398 (dubbed ‘clade (C)’) has spread within and between equine hospitals, where it causes nosocomial infections in horses and colonises the personnel.