Henrik Westh

TL;DR: WGS-based AST using ResFinder 4.0 provides in silico antibiograms as reliable as those obtained by phenotypic AST at least for the bacterial species/antimicrobial agents of major public health relevance considered.

TL;DR: Classification of staphylococcal cassette chromosome mec (S CCmec) : guidelines for reporting novel SCCmec elements.

TL;DR: The group consensus was to recommend spa and staphylococcal cassette chromosome mec (SCCmec) typing as the preferred methods for MRSA, which are informative in defining particular strain characteristics and utilise standardised nomenclatures, making them applicable globally.

TL;DR: The genetic changes associated with adaptation to the hospital environment and with increasing drug resistance over time are document, and how MRSA evolution likely has been influenced by country-specific drug use regimens are documented.

TL;DR: The genetic backgrounds and phenotypes of a group of methicillin-susceptible S. aureus isolates compared to the properties of MRSA strains isolated in Denmark and the U.K. during the same time period were compared, suggesting that genetic determinants present in early MSSA and essential for some aspects of the epidemicity and/or virulence of these strains may have been retained by this highly successful contemporary MRSA lineage.