F
Fraser Birrell
Researcher at Newcastle University
Publications - 103
Citations - 4416
Fraser Birrell is an academic researcher from Newcastle University. The author has contributed to research in topics: Osteoarthritis & Randomized controlled trial. The author has an hindex of 31, co-authored 98 publications receiving 3953 citations. Previous affiliations of Fraser Birrell include University of Nottingham & Newcastle upon Tyne Hospitals NHS Foundation Trust.
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Journal ArticleDOI
Evidence-based recommendations for the role of exercise in the management of osteoarthritis of the hip or knee—the MOVE consensus
Edward Roddy,Weiya Zhang,Michael Doherty,Nigel K Arden,Julie H. Barlow,Fraser Birrell,A Carr,K Chakravarty,John Dickson,Elaine M Hay,Gillian Hosie,Michael Hurley,K M Jordan,Christopher J. McCarthy,Marion E. T. McMurdo,Simon Mockett,S C O'Reilly,George Peat,Adrian Pendleton,Selwyn Richards +19 more
TL;DR: These are the first recommendations for exercise in hip and knee OA to clearly differentiate research evidence and expert opinion and to guide health-care practitioners.
Journal ArticleDOI
Identification of new susceptibility loci for osteoarthritis (arcOGEN): A genome-wide association study
Eleftheria Zeggini,Kalliope Panoutsopoulou,Lorraine Southam,Lorraine Southam,N W Rayner,Aaron G. Day-Williams,M C Lopes,M C Lopes,Vesna Boraska,Tõnu Esko,Evangelos Evangelou,A Hoffman,Jeanine J. Houwing-Duistermaat,Thorvaldur Ingvarsson,Ingileif Jonsdottir,Ingileif Jonsdottir,H Jonnson,Hanneke J. M. Kerkhof,Margreet Kloppenburg,Steffan D. Bos,Massimo Mangino,Sarah Metrustry,P E Slagboom,Gudmar Thorleifsson,Raine Eva.,Madhushika Ratnayake,Michelle Ricketts,C Beazley,Hannah Blackburn,Suzannah Bumpstead,K S Elliott,Sarah E. Hunt,Simon C. Potter,Shin S-Y.,Vijay K. Yadav,Guangju Zhai,K Sherburn,K Dixon,E Arden,N Aslam,Battley P-K.,I Carluke,Sally Doherty,Allan Gordon,J Joseph,Richard Keen,N Koller,Sheryl Mitchell,F O'Neill,E Paling,Mike R. Reed,Fernando Rivadeneira,D Swift,K Walker,Bridget Watkins,M. Wheeler,Fraser Birrell,Ioannidis Jpa.,Ingrid Meulenbelt,Andres Metspalu,Ashok Rai,Donald Salter,K. Stefansson,U Stykarsdottir,A.G. Uitterlinden,van Meurs Jbj.,Karen E. Chapman,Panagiotis Deloukas,Ollier Wer.,Gillian A. Wallis,Nigel K Arden,Andrew Carr,Michael Doherty,Andrew McCaskie,J M Willkinson,Stuart Ralston,Ana M. Valdes,Tim D. Spector,John Loughlin +78 more
TL;DR: One of the signals close to genome-wide significance was within the FTO gene, which is involved in regulation of bodyweight—a strong risk factor for osteoarthritis.
Journal ArticleDOI
Paracetamol: not as safe as we thought? A systematic literature review of observational studies
Emmert Roberts,Vanessa Delgado Nunes,Sara Buckner,Susan Latchem,Margaret Constanti,Paul D. Miller,Michael Doherty,Weiya Zhang,Fraser Birrell,Mark Porcheret,Krysia Dziedzic,Ian A. Bernstein,Elspeth Wise,Philip G. Conaghan +13 more
TL;DR: The dose–response seen for most endpoints suggests a considerable degree of paracetamol toxicity especially at the upper end of standard analgesic doses, and channelling bias may have had an important impact.
Journal ArticleDOI
British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of rheumatoid arthritis (after the first 2 years)
Raashid Luqmani,S Hennell,C Estrach,Fraser Birrell,A Bosworth,G Davenport,C Fokke,Nicola J Goodson,P Jeffreson,E Lamb,R Mohammed,S Oliver,Z Stableford,D Walsh,C Washbrook,F Webb +15 more
TL;DR: Guideline for the Management of Rheumatoid Arthritis (The first 2 years) R. Luqmani, S. Oliver, Z. Walsh, C. Washbrook and F. Webb on behalf of the British Society for rheumatology and British Health Professionals in R heumatology Standards, Guidelines and Audit Working Group.
Journal ArticleDOI
Projecting the need for hip replacement over the next three decades: influence of changing demography and threshold for surgery
TL;DR: A sharp rise in hip replacements will be needed to satisfy needs in the UK population over the next 30 years, and will be substantially higher in men than women.