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Garry P. Nolan
Researcher at Stanford University
Publications - 519
Citations - 54521
Garry P. Nolan is an academic researcher from Stanford University. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 104, co-authored 474 publications receiving 46025 citations. Previous affiliations of Garry P. Nolan include Massachusetts Institute of Technology & New York University.
Papers
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Journal Article
Phospho-specific flow cytometry: intersection of immunology and biochemistry at the single-cell level.
Matthew Hale,Garry P. Nolan +1 more
TL;DR: This review covers some of the most recent research to leverage flow cytometry for following intracellular signaling and follows two new developments: increasing interest in JAK/STAT signaling, and experimental strategies that reveal disease-induced modulation of signaling networks.
Journal ArticleDOI
Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells
Charis E Teh,Charis E Teh,Jia-Nan Gong,Jia-Nan Gong,David J. Segal,David J. Segal,Tania Tan,Cassandra J. Vandenberg,Cassandra J. Vandenberg,Pasquale L. Fedele,Pasquale L. Fedele,Michael Low,Michael Low,George Grigoriadis,George Grigoriadis,Simon J. Harrison,Simon J. Harrison,Andreas Strasser,Andreas Strasser,Andrew W. Roberts,David C.S. Huang,David C.S. Huang,Garry P. Nolan,Daniel H.D. Gray,Daniel H.D. Gray,Melissa E. Ko +25 more
TL;DR: The utility of CyTOF profiling at the single-cell level to identify clinically relevant drug combinations and tracking of patient responses for future clinical trials is demonstrated.
Patent
Use of bayesian networks for modeling cell signaling systems
TL;DR: In this article, a probabilistic graphical model of cellular networks is proposed for developing and using cellular networks by applying a Probabilistic Graphical Model (PGM) approach.
Patent
Combinatorial enzymatic complexes
Garry P. Nolan,Donald G. Payan +1 more
TL;DR: In this paper, the formation of novel in vivo combinatorial enzyme complexes for use in screening candidate drug agents for bioactivity is described, which relates to the creation of novel enzyme complexes.
Book ChapterDOI
Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis.
Felix J. Hartmann,Erin F. Simonds,Nora Vivanco,Trevor Bruce,Luciene Borges,Garry P. Nolan,Matthew H. Spitzer,Sean C. Bendall +7 more
TL;DR: Optimized and scalable protocols for conjugation of lanthanide as well as bismuth ions to immunoglobulin (Ig) using a maleimide-functionalized chelating polymer and for characterization of the conjugate are presented.