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Garry P. Nolan
Researcher at Stanford University
Publications - 519
Citations - 54521
Garry P. Nolan is an academic researcher from Stanford University. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 104, co-authored 474 publications receiving 46025 citations. Previous affiliations of Garry P. Nolan include Massachusetts Institute of Technology & New York University.
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Journal ArticleDOI
Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells.
TL;DR: This linkage in CLL B cells among the mechanisms governing chemotherapy-induced apoptosis increased signaling of BCR network proteins and a likely role of phosphatase activity suggests a means of stratifying patients for their response to F-ara-A based regimens.
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Retroviral technology--applications for expressed peptide libraries.
Roland Wolkowicz,Garry P. Nolan +1 more
TL;DR: Novel high-throughput approaches might allow for the rapid creation of small-molecule switches in protein-protein interactions and as such the expression of small molecules that will have a specific biological outcome can become an answer to queries.
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Enzyme-generated intracellular fluorescence for single-cell reporter gene analysis utilizing Escherichia coli β-glucuronidase
TL;DR: A new fluorescence-activated cell sorter (FACS)-based reporter gene system utilizing the enzymatic activity of the E. coli beta-glucuronidase gene, which has high specificities for their cognate substrates, allowing each reporter gene to be measured by FACS independently.
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Landscape of coordinated immune responses to H1N1 challenge in humans.
Zainab Rahil,Rebecca Leylek,Christian M. Schürch,Han Chen,Zach Bjornson-Hooper,Shannon R. Christensen,Pier Federico Gherardini,Salil S. Bhate,Matthew H. Spitzer,Gabriela K. Fragiadakis,Nilanjan Mukherjee,Nelson Kim,Sizun Jiang,Jennifer Yo,Brice Gaudilliere,Melton Affrime,Bonnie Bock,Scott E. Hensley,Juliana Idoyaga,Nima Aghaeepour,Kenneth Kim,Garry P. Nolan,David R. McIlwain +22 more
TL;DR: The coordinated immune cell dynamics defined in this study provide a framework for identifying novel correlates of protection in the evaluation of future influenza therapeutics and Machine learning using study-derived clinical parameters and single-cell data effectively classified and predicted susceptibility to infection.
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Functional comparison of PBMCs isolated by Cell Preparation Tubes (CPT) vs. Lymphoprep Tubes
Han Chen,Christian M. Schürch,Kevin Noble,Kenneth Kim,Peter O. Krutzik,Erika A. O'Donnell,Jason Vander Tuig,Garry P. Nolan,David R. McIlwain +8 more
TL;DR: CPT and Lymphoprep tubes are effective and comparable methods for PBMC isolation for immunological studies and no significant differences in cell recovery, viability, frequency of immune cell subsets, or T cell functionality between PBMC samples isolated using CPT or LymphOPrep tubes were identified.