G
Garry P. Nolan
Researcher at Stanford University
Publications - 519
Citations - 54521
Garry P. Nolan is an academic researcher from Stanford University. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 104, co-authored 474 publications receiving 46025 citations. Previous affiliations of Garry P. Nolan include Massachusetts Institute of Technology & New York University.
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Journal ArticleDOI
The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner.
Garry P. Nolan,T. Fujita,Kishor Bhatia,Conrad Huppi,Hsiou-Chi Liou,Martin L. Scott,David Baltimore +6 more
TL;DR: Bcl-3 appears to be a nuclear, I kappa B-related molecule that regulates the activity of homodimeric nuclear p50 and its homolog p52, and partially inactivated its inhibitory properties, implicating a role for phosphorylation in the regulation of B cl-3 activity.
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Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette.
TL;DR: The current cassette of the retroviral construct (SIN-RetroTet vector) allows rapid delivery of inducible genes and should have broad applications to cultured cells, transgenic animals, and gene therapy.
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Host Control of HIV-1 Parasitism in T Cells by the Nuclear Factor of Activated T Cells
TL;DR: T cells can become competent for HIV-1 replication by control of regulated host factors such as the NFATc transcription factor, and the host mechanisms regulated by such permissivity factors are potential targets for anti-HIV-1 therapy.
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Single Cell Profiling Identifies Aberrant STAT5 Activation in Myeloid Malignancies with Specific Clinical and Biologic Correlates
Nikesh Kotecha,Nikki J. Flores,Jonathan M. Irish,Erin F. Simonds,Debbie S Sakai,Sophie Archambeault,Ernesto Diaz-Flores,Marc Coram,Kevin Shannon,Garry P. Nolan,Mignon L. Loh +10 more
TL;DR: Using flow cytometry, a specific evoked STAT5 signaling signature was observed in a subset of samples from patients suspected of having juvenile myelomonocytic leukemia, suggesting a critical role of this pathway in the biological mechanism of this disorder and indicating potential targets for future therapies.
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Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells.
Yasumichi Hitoshi,James Lorens,Shinichi Kitada,Joan M. Fisher,Mark A. LaBarge,Huijun Z. Ring,Uta Francke,John C. Reed,Shigemi Kinoshita,Garry P. Nolan +9 more
TL;DR: Toso serves as a novel regulator of Fas-mediated apoptosis and may act as a regulator of cell fate in T cells and other hematopoietic lineages.