G
Garry P. Nolan
Researcher at Stanford University
Publications - 519
Citations - 54521
Garry P. Nolan is an academic researcher from Stanford University. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 104, co-authored 474 publications receiving 46025 citations. Previous affiliations of Garry P. Nolan include Massachusetts Institute of Technology & New York University.
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Proteomics and genomics: The emergent properties of biomarkers in mechanism and medicine
Patent
Methods and compositions for risk stratification
TL;DR: In this article, an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells is presented, which permits the rapid detection of heterogeneity in a complex cell population based on activation states, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population.
Journal ArticleDOI
Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis
Catherine M. Shachaf,Omar D. Perez,Sawsan Youssef,Alice C. Fan,Sailaja Elchuri,Matthew J. Goldstein,Amy E. Shirer,Orr Sharpe,Joy Chen,Dennis J. Mitchell,Maria Chang,Garry P. Nolan,Lawrence Steinman,Dean W. Felsher +13 more
TL;DR: It is demonstrated in an in vivo transgenic model in which atorvastatin reverses and prevents the onset of MYC-induced lymphomagenesis, but fails to reverse or prevent tumorigenesis in the presence of constitutively activated K-Ras.
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Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity.
Lu Cui,Shih-Yu Chen,Tristan Lerbs,Jin-Wook Lee,Pablo Domizi,Sydney Gordon,Yong-hun Kim,Garry P. Nolan,Paola Betancur,Gerlinde Wernig +9 more
TL;DR: An overall immune suppressive environment transcriptionally controlled and maintained by fibroblasts in lung fibrosis with possible therapeutic implications is shown.
Journal ArticleDOI
Treatment of autoimmune disease by adoptive cellular gene therapy.
Ingo H. Tarner,Anthony J. Slavin,Jacqueline McBride,Alenka Levicnik,Richard Smith,Garry P. Nolan,Christopher H. Contag,C. Garrison Fathman +7 more
TL;DR: It is demonstrated that primary T cells, T cell hybridomas, and DCs rapidly and preferentially home to the sites of inflammation in animal models of multiple sclerosis, arthritis, and diabetes.