G
Garry P. Nolan
Researcher at Stanford University
Publications - 519
Citations - 54521
Garry P. Nolan is an academic researcher from Stanford University. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 104, co-authored 474 publications receiving 46025 citations. Previous affiliations of Garry P. Nolan include Massachusetts Institute of Technology & New York University.
Papers
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Journal ArticleDOI
Single Cell Mass Cytometry Reveals Hyperactivated Signaling Networks in Myeloproliferative Neoplasms
Daniel A.C. Fisher,Olga Malkova,Mary C. Fulbright,Gregory K. Behbehani,Garry P. Nolan,Stephen T. Oh +5 more
TL;DR: The findings suggest that co-targeting of JAK2 and NFκB could be beneficial therapeutically and suggest an extensive network of hyperactivated signaling in MF and sAML HSPCs, which may represent targets for improved therapeutic intervention.
Journal ArticleDOI
Author Correction: Ultra-high throughput single-cell analysis of proteins and RNAs by split-pool synthesis.
Maeve O'Huallachain,Felice-Alessio Bava,Mary Shen,Carolina Dallett,Sri Paladugu,Nikolay Samusik,Nikolay Samusik,Simon Yu,Razika Hussein,Grantland Hillman,Samuel Higgins,Melanie Lou,Angelica Trejo,Laura Qin,Yu Chuan Tai,Shigemi M. Kinoshita,Astraea Jager,Deval Lashkari,Yury Goltsev,Sedide Ozturk,Garry P. Nolan +20 more
TL;DR: An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Book ChapterDOI
Intracellular Combinatorial Chemistry with Peptides in Selection of Caspase-like Inhibitors
S. Michael Rothenberg,Joan M. Fisher,David Zapol,David C. Anderson,Yasumichi Hitoshi,Philip Achacoso,Garry P. Nolan +6 more
TL;DR: Using a retroviral expression system, a short peptide derived from the cleavage site in a cellular target of a pro-apoptotic cysteine protease can be expressed within intact cells with sufficient activity to inhibit Fas-mediated apoptosis.
Journal ArticleDOI
233: Multiparametric high dimensional analysis of normal & VZV infected human tonsil T cells at a single cell resolution by mass cytometry
Nandini Sen,Gourab Mukherjee,Sean C. Bendall,Adrish Sen,Astraea Jager,Phil Sung,Garry P. Nolan,Iain M. Johnstone,Ann M. Arvin +8 more
TL;DR: In context of infection, there was decreased expression of CD3 and increased expression of PD-1 and CD69 on infected cells correlating with increased phosphorylation of proteins in the TCR pathway similar to changes observed during T cell activation, and infected naive T cells appeared to be transitioning to the memory-like phenotype.
Journal ArticleDOI
Inner-outer beauty: DNA-binding surface tags as cellular barcodes
TL;DR: Zinc-finger DNA-binding domains are expressed on the surface of cells so that the cells can be tagged with fluorescently labeled oligonucleotides, enabling many possible applications in complex cell populations.