L
Leonid Churilov
Researcher at University of Melbourne
Publications - 529
Citations - 17307
Leonid Churilov is an academic researcher from University of Melbourne. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 45, co-authored 467 publications receiving 13155 citations. Previous affiliations of Leonid Churilov include Monash University, Clayton campus & Florey Institute of Neuroscience and Mental Health.
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Journal ArticleDOI
Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection
Bruce C.V. Campbell,Leonid Churilov,Nawaf Yassi,Bernard Yan,M. Brooks,F. Miteff,Martin Krause,M. Priglinger,Timothy Ang,Rebecca Scroop,Ben McGuinness,Tissa Wijeratne,Winston Chong,Monica S Badve,H. Rice,L. de Villiers,Henry Ma,Abstr Act +17 more
TL;DR: In patients with ischemic stroke with a proximal cerebral arterial occlusion and salvageable tissue on CT perfusion imaging, early thrombectomy with the Solitaire FR stent retriever, as compared with alteplase alone, improved reperfusion, early neurologic recovery, and functional outcome.
Journal ArticleDOI
Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial
Julie Bernhardt,Peter Langhorne,Richard I. Lindley,Amanda G. Thrift,Fiona Ellery,Janice Collier,Leonid Churilov,Marjory Moodie,Helen M Dewey,Geoffrey A. Donnan +9 more
TL;DR: The higher dose, very early mobilisation protocol was associated with a reduction in the odds of a favourable outcome at 3 months and should affect clinical practice by refining present guidelines; however, clinical recommendations should be informed by future analyses of dose-response associations.
Journal ArticleDOI
Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke
Bruce C.V. Campbell,Peter Mitchell,Leonid Churilov,Nawaf Yassi,Timothy Kleinig,Richard Dowling,Bernard Yan,Steven Bush,Helen M Dewey,Vincent Thijs,Vincent Thijs,Rebecca Scroop,Marion Simpson,Mark Brooks,Hamed Asadi,Hamed Asadi,Hamed Asadi,Teddy Y. Wu,Teddy Y. Wu,Darshan Shah,Darshan Shah,Tissa Wijeratne,Timothy Ang,Ferdinand Miteff,Christopher R Levi,Edrich Rodrigues,Henry Zhao,Patrick Salvaris,Carlos Garcia-Esperon,Peter L. Bailey,Henry E. Rice,Laetitia de Villiers,Helen Brown,Kendal Redmond,David Leggett,John N. Fink,Wayne Collecutt,Andrew Wong,Claire Muller,Alan Coulthard,Ken Mitchell,John Clouston,Kate Mahady,Deborah Field,Henry Ma,Thanh G. Phan,Winston Chong,Ronil V. Chandra,Lee-Anne Slater,Martin Krause,Timothy Harrington,Timothy Harrington,Kenneth Faulder,Kenneth Faulder,Brendan Steinfort,Brendan Steinfort,Christopher F. Bladin,Christopher F. Bladin,Gagan Sharma,Patricia Desmond,Mark W Parsons,Geoffrey A. Donnan,Stephen M. Davis +62 more
TL;DR: Tenecteplase before thrombectomy was associated with a higher incidence of reperfusion and better functional outcome than alteplase among patients with ischemic stroke treated within 4.5 hours after symptom onset.
Journal ArticleDOI
Standardized measurement of sensorimotor recovery in stroke trials: consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable
Gert Kwakkel,Natasha A. Lannin,Karen Borschmann,Coralie English,Myzoon Ali,Myzoon Ali,Leonid Churilov,Gustavo Saposnik,Carolee J. Winstein,Erwin E. H. van Wegen,Steven L. Wolf,John W. Krakauer,Julie Bernhardt +12 more
TL;DR: The results of a consensus meeting about measurement standards and patient characteristics that should be collected in all future stroke recovery trials are presented and a strong case is made for addition of kinematic and kinetic movement quantification.
Journal ArticleDOI
Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data
Bruce C.V. Campbell,Bruce C.V. Campbell,Henry Ma,Henry Ma,Peter A. Ringleb,Mark W Parsons,Leonid Churilov,Martin Bendszus,Christopher R Levi,Chung Hsu,Timothy Kleinig,Marc Fatar,Didier Leys,Carlos A. Molina,Tissa Wijeratne,Sami Curtze,Helen M Dewey,P. Alan Barber,Kenneth Butcher,Kenneth Butcher,Deidre A De Silva,Christopher F. Bladin,Christopher F. Bladin,Nawaf Yassi,Nawaf Yassi,Johannes Pfaff,Gagan Sharma,Andrew Bivard,Patricia Desmond,Stefan Schwab,Peter D Schellinger,Bernard Yan,Peter Mitchell,Joaquín Serena,Danilo Toni,Vincent Thijs,Vincent Thijs,Werner Hacke,Stephen M. Davis,Geoffrey A. Donnan,Geoffrey A. Donnan,Thomas J Oxley,Teddy Y. Wu,Darshan Shah,Henry Zhao,Edrich Rodrigues,Patrick Salvaris,Fana Alemseged,Felix C Ng,Cameron Williams,Jo-Lyn Ng,Hans T.H. Tu,Amy A. McDonald,David C. Jackson,Jessica Tsoleridis,Rachael McCoy,Lauren Pesavento,Louise Weir,Sandy Patel,John T Harvey,Jeyaledchumy Mahadevan,E. Cheong,Anna H. Balabanski,Michael J. Waters,Roy Drew,Jennifer Cranefield,Elizabeth Mackey,Sherisse Celestino,Essie Low,Poh Sien Loh,Philip M.C. Choi,Skye Coote,Tanya Frost,K. Hogan,C. Ding,S. McModie,W.W. Zhang,Christopher Kyndt,A. Moore,Z. Ross,J. Liu,Ferdinand Miteff,Timothy Ang,Neil J. Spratt,Carlos Garcia-Esperon,Lara Kaauwai,Thanh G. Phan,John Ly,Shaloo Singhal,Benjamin Clissold,Kitty Wong,Martin Krause,Susan Day,Jonathan Sturm,Bill O'Brian,Rohan Grimley,Marion Simpson,Matthew Lee-Archer,Amy Brodtmann,Bronwyn Coulton,Dennis Young,Andrew Wong,Claire Muller,Deborah Field,Wilson Vallat,Vanessa Maxwell,Peter L. Bailey,Arman Sabet,Sachin Mishra,Meng Tan,K. George,L. Zhao,Atte Meretoja,Turgut Tatlisumak,Gerli Sibolt,Marjaana Tiainen,M. Koivu,Karoliina Aarnio,J. Virta,O. Kasari,S. Eirola,M.C. Sun,T.C. Chen,C.S. Chuang,Y.Y. Chen,C.M. Lin,S.C. Ho,P.M. Hsiao,C.H. Tsai,W.S. Huang,Y.W. Yang,H.Y. Huang,W.C. Wang,C.H. Liu,M.K. Lu,C.H. Lu,W.L. Kung,S.K. Jiang,Y.H. Wu,S.C. Huang,C.H. Tseng,L.T. Tseng,Y.C. Guo,D. Lin,C. T. Hsu,C.W. Kuan,J.P. Hsu,H.T. Tsai,M. Suzuki,Y. Sun,H.F. Chen,C.J. Lu,C.H. Lin,C.C. Huang,H.J. Chu,Cheryl Yi-Pin Lee,W.H. Chang,Y.C. Lo,Y.T. Hsu,C.H. Chen,P.S. Sung,C. L. Ysai,J.S. Jeng,S.C. Tang,Li-Kai Tsai,S.J. Yeh,Y.C. Lee,Y.T. Wang,T.C. Chung,C.J. Hu,L. Chan,Y.W. Chiou,L.M. Lien,H.L. Yeh,J.H. Yeh,W.H. Chen,C.L. Lau,A. Chang,I.Y. Lee,M.Y. Huang,J.T. Lee,G.S. Peng,J.C. Lim,Y.D. Hsu,C.C. Lin,C.A. Cheng,C.H. Yen,F.C. Yang,C.H. Hsu,Y.F. Sung,C.K. Tsai,C.L. Tsai,A. Lee,Graeme J. Hankey,David Blacker,Richard P. Gerraty,C-I. Chen,C-S. Hsu,Elise Cowley,Michele Sallaberger,Barry Snow,John Kolbe,Richard J Stark,John King,Richard Macdonnell,John Attia,Catherine D'Este,Julie Bernhardt,Leeanne M. Carey,Dominique A Cadilhac,Craig S. Anderson,David W. Howells,Alan Barber,Alan Connelly,Malcolm R. Macleod,Victoria E O'Collins,William Wilson,Lance Macaulay,Erich Bluhmki,Christoph C. Eschenfelder,Peter A. Ringleb,Peter D. Schellinger,Nils Wahlgren,Joanna M. Wardlaw,Catherine Oppenheim,Kennedy R. Lees,Markku Kaste,Rüdiger von Kummer,Gilles Chatellier,Rico Laage,Xavier Nuñez,Christina Ehrenkrona,Ann-Sofie Svenson,Lynda Cove,Kurt Niederkorn,Franz Gruber,Peter Kapeller,Robert Mikulik,Jean-Louis Mas,Jörg Berrouschot,Jan Sobesky,Martin Köhrmann,Thorsten Steiner,Christof Kessler,Rainer Dziewas,Sven Poli,Katharina Althaus-Knaurer,Paolo Bovi,Alain Luna Rodriguez,Juan F. Arenillas,Keith W. Muir,Roland Veltkamp,Anand Dixit,Girish Muddegowda,Lalit Kala,Graham Byrnes,André Peeters,J. Chalk,John N. Fink,Thomas E. Kimber,David Schultz,Peter J. Hand,Judith Frayne,Brian M. Tress,John J McNeil,R. Burns,C. Johnston,Michael Williams +267 more
TL;DR: Patients with ischaemic stroke 4·5-9 h from stroke onset or wake-up stroke with salvageable brain tissue who were treated with alteplase achieved better functional outcomes than did patients given placebo, and this increase in the rate of symptomatic intracerebral haemorrhage did not negate the overall net benefit of thrombolysis.