G
Georg N. Duda
Researcher at Charité
Publications - 613
Citations - 31004
Georg N. Duda is an academic researcher from Charité. The author has contributed to research in topics: Bone healing & Bone regeneration. The author has an hindex of 81, co-authored 563 publications receiving 25802 citations. Previous affiliations of Georg N. Duda include Humboldt University of Berlin & University of Ulm.
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Promiscuous and depolarization-induced immediate-early response genes are induced by mechanical strain of osteoblasts.
Claus-Eric Ott,Sebastian Bauer,Thomas Manke,Susan Ahrens,Christian Rödelsperger,Johannes Grünhagen,Uwe Kornak,Georg N. Duda,Stefan Mundlos,Peter N. Robinson +9 more
TL;DR: The results showed the existence of two distinct pathways that mediate the IER of osteoblasts to large‐magnitude mechanical straining and suggest that the I ER to depolarizing stimuli is conserved in cell types as different as osteoblast and neurons.
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Surgical approach influences periprosthetic femoral bone density
Carsten Perka,Markus O. Heller,Katja Wilke,William R. Taylor,Norbert Haas,Hartmut Zippel,Georg N. Duda +6 more
TL;DR: In this paper, the bone mineral density of the proximal femur is altered significantly by surgical approach and a potential reason for the bone density shift might have been a redistribution of the musculoskeletal loading across the hip after a transgluteal, compared with an anterolateral, surgical approach.
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Semi-rigid screws provide an auxiliary option to plate working length to control interfragmentary movement in locking plate fixation at the distal femur.
Mark Heyland,Georg N. Duda,Norbert P. Haas,Adam Trepczynski,Stefan Döbele,Dankward Höntzsch,Klaus-Dieter Schaser,Sven Märdian +7 more
TL;DR: Mechanical frame conditions can be significantly influenced by type and placement of the screws in locking plate osteosynthesis of the distal femur by varying plate working length stiffness and IFM are modulated.
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Immune Modulation to Enhance Bone Healing-A New Concept to Induce Bone Using Prostacyclin to Locally Modulate Immunity.
Sebastian Wendler,Claudia Schlundt,Christian H. Bucher,Jan Birkigt,Christian J. Schipp,Hans-Dieter Volk,Georg N. Duda,Katharina Schmidt-Bleek +7 more
TL;DR: The presented data confirms a possible strategy to modulate the early inflammatory phase in aged individuals toward a physiological healing by a downregulation of an excessive pro-inflammation that otherwise would impair healing.
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Immediate and delayed transplantation of mesenchymal stem cells improve muscle force after skeletal muscle injury in rats
Tobias Winkler,Philipp von Roth,Piotr Radojewski,Alexander Urbanski,Sebastian Hahn,Bernd Preininger,Georg N. Duda,Carsten Perka +7 more
TL;DR: It is believed that transplanted MSCs residing in the interstitial compartment evolve their regenerative capabilities through paracrine pathways, similar results could be obtained with respect to functional muscle regeneration.