G
Georg N. Duda
Researcher at Charité
Publications - 613
Citations - 31004
Georg N. Duda is an academic researcher from Charité. The author has contributed to research in topics: Bone healing & Bone regeneration. The author has an hindex of 81, co-authored 563 publications receiving 25802 citations. Previous affiliations of Georg N. Duda include Humboldt University of Berlin & University of Ulm.
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Bone healing in mice: does it follow generic mechano-regulation rules?
TL;DR: It is suggested that in mice, bone does not require as much stability as is required in rat to reach timely healing, emphasizing the need to further investigate the species-specific mechano-biological regulation of bone regeneration.
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Sost deficiency leads to reduced mechanical strains at the tibia midshaft in strain-matched in vivo loading experiments in mice.
Laia Albiol,Myriam Cilla,David Pflanz,Ina Kramer,Michaela Kneissel,Georg N. Duda,Bettina M. Willie,Bettina M. Willie,Sara Checa +8 more
TL;DR: The local mechanical environment in the bone was analysed using finite-element models (FEMs), which showed that strains in the tibiae of Sost KO mice are lower than in age-matched LC mice at the diaphyseal midshaft, a region commonly used to assess cortical bone formation and resorption.
Journal Article
Effects of dexamethasone and celecoxib on calcium homeostasis and expression of cyclooxygenase-2 mRNA in MG-63 human osteosarcoma cells.
Wiontzek M,Georg Matziolis,Sebastian Schuchmann,Timo Gaber,D. Krocker,Georg N. Duda,G.-R. Burmester,C. Perka,Frank Buttgereit +8 more
TL;DR: Dexamethasone was found to inhibit the [Ca2+]i increase in MG-63 cells following stimulation and to reduce considerably COX-2 expression via the genomic pathway, while celecoxib did not show any measurable short-term or long-term effects on the parameters of bone physiology measured.
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CD133: enhancement of bone healing by local transplantation of peripheral blood cells in a biologically delayed rat osteotomy model.
Bernd Preininger,Georg N. Duda,Hinnerk Gerigk,Jonas Bruckner,Agnes Ellinghaus,F. Andrea Sass,Carsten Perka,Katharina Schmidt-Bleek,Anke Dienelt +8 more
TL;DR: This study demonstrates the suitability of angiogenic precursors to further bone healing and gives an indication that peripheral blood is a promising source for progenitor cells circumventing the problems associated with bone marrow extraction.
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Endogenous musculoskeletal tissue regeneration.
TL;DR: This special issue aims at reviewing recent scientific developments in the field of musculoskeletal regeneration and at identifying clinical challenges associated with augmenting or stimulating endogenous repair processes and restoring function to musculOSkeletal tissues.