G
Georg N. Duda
Researcher at Charité
Publications - 613
Citations - 31004
Georg N. Duda is an academic researcher from Charité. The author has contributed to research in topics: Bone healing & Bone regeneration. The author has an hindex of 81, co-authored 563 publications receiving 25802 citations. Previous affiliations of Georg N. Duda include Humboldt University of Berlin & University of Ulm.
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A method to determine the 3-D stiffness of fracture fixation devices and its application to predict inter-fragmentary movement
TL;DR: A 6 x 6 stiffness matrix is introduced which completely describes the linear relationship between the 6 inter-fragmentary movements and the resulting bony loading (3 forces and 3 moments) and the authors conclude that a single value is not sufficient to describe the mechanical relationship.
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Composite transcriptome assembly of RNA-seq data in a sheep model for delayed bone healing
Marten Jäger,Claus-Eric Ott,Johannes Grünhagen,Jochen Hecht,Jochen Hecht,Hanna Schell,Stefan Mundlos,Stefan Mundlos,Georg N. Duda,Peter N. Robinson,Peter N. Robinson,Jasmin Lienau +11 more
TL;DR: A first atlas of gene expression profiles and differentially expressed genes in standard and delayed bone healing in a large-animal model is provided and a number of clues as to the shifts in gene expression that underlie delayedBone healing are provided.
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Geometry-driven cell organization determines tissue growths in scaffold pores: consequences for fibronectin organization
Pascal Joly,Georg N. Duda,Martin Schöne,Petra B. Welzel,Petra B. Welzel,Uwe Freudenberg,Uwe Freudenberg,Carsten Werner,Carsten Werner,Ansgar Petersen +9 more
TL;DR: Scaffold pore size directed the time required for pore closure and furthermore impacted the organization of the fibronectin matrix, indicating a reorganization of the cell/ECM network.
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Mechanical induction of critically delayed bone healing in sheep: Radiological and biomechanical results
Hanna Schell,Mark S. Thompson,Hermann J. Bail,Jan-Erik Hoffmann,Alexander Schill,Georg N. Duda,Jasmin Lienau +6 more
TL;DR: The presented ovine model provides the basis for a comparative evaluation of mechanisms controlling delayed and standard bone healing and led to the development of a hypertrophic non-union in sheep.
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The multifaceted roles of macrophages in bone regeneration: A story of polarization, activation and time
Claudia Schlundt,Heilwig Fischer,Christian H. Bucher,Carsten Rendenbach,Georg N. Duda,Katharina Schmidt-Bleek +5 more
TL;DR: In this paper, the authors discuss the high degree of plasticity of macrophages and the relevant contribution of the different and more specific M2 subtypes (M2a-M2f) during bone regeneration.