G
Georg N. Duda
Researcher at Charité
Publications - 613
Citations - 31004
Georg N. Duda is an academic researcher from Charité. The author has contributed to research in topics: Bone healing & Bone regeneration. The author has an hindex of 81, co-authored 563 publications receiving 25802 citations. Previous affiliations of Georg N. Duda include Humboldt University of Berlin & University of Ulm.
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Analysis of inter-fragmentary movement as a function of musculoskeletal loading conditions in sheep
Georg N. Duda,Kerstin Eckert-Hübner,Roman Sokiranski,Albert Kreutner,Rudolf Miller,Lutz Claes +5 more
TL;DR: A 3D musculoskeletal model of the left hind limb of a sheep and results suggest that inter-fragmentary movement of metatarsal fractures is fairly independent of the fracture location whereas the movement increases in proximal tibial fractures compared to those in the distal and diaphyseal tibia.
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Matrix metalloprotease activity is an essential link between mechanical stimulus and mesenchymal stem cell behavior.
Grit Kasper,Juliane D. Glaeser,Juliane D. Glaeser,Sven Geissler,Andrea Ode,Jens Tuischer,Georg Matziolis,Carsten Perka,Georg N. Duda +8 more
TL;DR: The results of this study suggest that MSC function is controlled by MMP activity, which in turn is regulated by mechanical stimulation of cells, and MMP/TIMP balance seems to play an essential role in transferring mechanical signals into M SC function.
Osteoclastic activity begins early and increases over the course of bone healing
Hanna Schell,Jasmin Lienau,Devakara R. Epari,Petra Seebeck,Christine Exner,Sarah Muchow,Hermann Bragulla,Norbert Haas,Georg N. Duda +8 more
TL;DR: In this paper, the osteoclastic number was counted, the area of mineralised bone tissue was measured histomorphometrically and density of osteoclasts per square millimetre mineralised tissue was calculated.
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Angle stable locking reduces interfragmentary movements and promotes healing after unreamed nailing. Study of a displaced osteotomy model in sheep tibiae.
Katharina Kaspar,Hanna Schell,Petra Seebeck,Mark S. Thompson,Michael Schütz,Norbert Haas,Georg N. Duda +6 more
TL;DR: In this article, the authors investigated the effect of angle stable tibial nails on the bone-healing of an osteotomy site following stabilization with unreamed nailing.
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Spatial and temporal variations of mechanical properties and mineral content of the external callus during bone healing.
Inderchand Manjubala,Yifei Liu,Devakara R. Epari,Paul Roschger,Hanna Schell,Peter Fratzl,Georg N. Duda +6 more
TL;DR: The spatial and temporal distribution of mineral content and the nanoindentation modulus of the callus formed via intramembranous ossification over the course of bone healing are correlated to illustrate the ongoing remodelling process observed from histological analysis.