Georg N. Duda

TL;DR: In this study, amino-polyvinyl alcohol coated (A-PVA) SPIONs are introduced for cell-labeling and visualization by magnetic resonance imaging (MRI) of human MSCs and are found to be non-toxic to M SCs and non-destructive towards their multi-lineage differentiation potential.

TL;DR: This work phenotype the phases of vascular regeneration—the expansion phase (d1–d7 after injury) and the remodeling phase of the endothelial network, until tissue integrity is restored (d14–d21 after injury).

TL;DR: The data indicate that bone fragility in NF1 tibial dysplasia is partly due to an increased osteocyte-related micro-porosity, hypomineralization, a generalized defect of organic matrix formation, exacerbated in the regions of tensional and bending force integration, and finally persistence of ectopic blood vessels associated with localized macro-porotic bone lesions.

TL;DR: Evidence is provided that subject specific loading conditions and physiological boundary constraints are essential for explaining inter-patient variations in bone adaptation patterns and improved knowledge of the rules governing the adaptation of bone following THA helps towards understanding the interplay between mechanics and biology.

TL;DR: TBI results in an increased formation of callus and mineral density compared to normal bone healing in mice, and this fact combined with a tendency towards accelerated gap bridging leads to increased torsional strength.