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Grace J. Young
Researcher at University of Bristol
Publications - 39
Citations - 930
Grace J. Young is an academic researcher from University of Bristol. The author has contributed to research in topics: Randomized controlled trial & Lower urinary tract symptoms. The author has an hindex of 11, co-authored 33 publications receiving 577 citations.
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Journal ArticleDOI
Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial
Richard M. Martin,Richard M. Martin,Jenny L Donovan,Jenny L Donovan,Emma L Turner,Chris Metcalfe,Grace J. Young,Eleanor I Walsh,J. Athene Lane,Sian Noble,Steven E. Oliver,Simon Evans,Jonathan A C Sterne,Jonathan A C Sterne,Peter Holding,Yoav Ben-Shlomo,Yoav Ben-Shlomo,Peter Brindle,Naomi J Williams,Elizabeth M Hill,Siaw Yein Ng,Jessica Toole,Marta Tazewell,Laura J Hughes,Charlotte F Davies,Joanna Thorn,Elizabeth Down,George Davey Smith,David E. Neal,David E. Neal,Freddie C. Hamdy +30 more
TL;DR: There was no significant difference in prostate cancer mortality after a median follow-up of 10 years but the detection of low-risk prostate cancer cases increased and the findings do not support single PSA testing for population-based screening.
Journal ArticleDOI
Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received
David E. Neal,Chris Metcalfe,Jenny L Donovan,J. Athene Lane,Michael Davis,Grace J. Young,Susan J Dutton,Eleanor I. Walsh,Richard M. Martin,Tim J Peters,Emma L Turner,Malcolm David Mason,Richard J. Bryant,Prasad Bollina,James W.F. Catto,Alan Doherty,David Gillatt,Vincent J. Gnanapragasam,Peter Holding,Owen Hughes,Roger Kockelbergh,Howard Kynaston,Jon Oxley,Alan Paul,Edgar Paez,Derek J. Rosario,Edward Rowe,John Staffurth,Doug G Altman,Freddie C. Hamdy,Andrew Doble,Philip Powell,Stephen Prescott,Derek Rosario,John Anderson,Jonathan Aning,Garett Durkan,Anthony Koupparis,Hing Y. Leung,Param Mariappan,Alan McNeill,Raj Persad,Hartwig Schwaibold,David N. Tulloch,Michael Wallace,Susan Bonnington,Lynne Bradshaw,Deborah Cooper,Emma Elliott,Phillipa Herbert,Joanne Howson,Amanda Jones,T Lennon,Norma Lyons,Hilary Moody,Claire Plumb,Tricia O'Sullivan,Elizabeth Salter,Pauline Thompson,Sarah Tidball,Jan Blaikie,Catherine Gray,Tonia Adam,Sarah Askew,Sharon Atkinson,Tim Baynes,Carole Brain,Viv Breen,Sarah Brunt,Sean Bryne,Jo Bythem,Jenny Clarke,Jenny Cloete,Susan Dark,Gill Davis,Rachael De La Rue,Jane Denizot,Elspeth Dewhurst,Anna Dimes,Nicola Dixon,Penny Ebbs,Ingrid Emmerson,Jill Ferguson,Ali Gadd,Lisa Geoghegan,Alison Grant,Collette Grant,Rosemary Godfrey,Louise Goodwin,Susie Hall,Liz Hart,Andrew Harvey,Chloe Hoult,Sarah Hawkins,Sharon Holling,Alastair Innes,Sue Kilner,Fiona Marshall,Louise Mellen,Andrea Moore,Sally Napier,Julie Needham,Kevin Pearse,Anna Pisa,Mark Rees,Ellie Richards,Lindsay Robson,Janet Roxburgh,Nikki Samuel,Irene Sharkey,Michael Slater,D. J. Smith,Pippa Taggart,Helen Taylor,Vicky Taylor,Ayesha Thomas,Briony Tomkies,Nicola Trewick,Claire Ward,Christy Walker,Ayesha Williams,C.R.J. Woodhouse,Elizabeth Wyber,Amit Bahl,Richard Benson,Mark Beresford,C.L. Ferguson,John Graham,Chris Herbert,Grahame Howard,Nicholas D. James,Peter Kirkbride,Alastair Law,Carmel Loughrey,Duncan McClaren,Helen Patterson,Ian Pedley,Trevor Roberts,Angus Robinson,Simon Russell,P. Symonds,Narottam Thanvi,Subramaniam Vasanthan,Paula Wilson,M.C. Robinson,Selina Bhattarai,Neeta Deshmukh,John Dormer,Malee Fernando,John R. Goepel,David J. Griffiths,Ken Grigor,Nick Mayer,Murali Varma,Anne Y. Warren,Helen Appleby,Dominic Ash,Dean Aston,Steven Bolton,Graham Chalmers,John Conway,Nick Early,Tony Geater,Lynda Goddall,Claire Heymann,Deborah Hicks,Liza Jones,Susan Lamb,Geoff Lambert,Gill Lawrence,Geraint Lewis,John Lilley,Aileen MacLeod,Pauline Massey,Alison McQueen,Rollo Moore,Lynda Penketh,Janet Potterton,Neil Roberts,Helen Showler,Pam Shuttleworth,Stephen Slade,Alasdair Steele,James Swinscoe,Marie Tiffany,John Townley,Jo Treeby,Michael Weston,Joyce Wilkinson,Lorraine Williams,Lucy Wills,O. Woodley,Sue Yarrow,Lucy Brindle,Linda Davies,D J Dedman,Elizabeth Down,Hanan Khazragui,Sian Noble,Hilary Taylor,Marta Tazewell,Julia Wade,Eleanor I Walsh,Susan Baker,Elizabeth Bellis-Sheldon,Chantal Bougard,Joanne Bowtell,Catherine Brewer,Chris Burton,Jennie Charlton,Nicholas Christoforou,Rebecca Clark,Susan Coull,Christine Croker,Rosemary Currer,Claire Daisey,Gill Delaney,Rose Donohue,Jane Drew,Rebecca Farmer,Susan Fry,Jean Haddow,Alex Hale,Susan Halpin,Belle Harris,Barbara Hattrick,Sharon Holmes,Helen Hunt,Vicky Jackson,Donna Johnson,Mandy Le Butt,Jo Leworthy,Tanya Liddiatt,Alex Martin,Jainee Mauree,Susan Moore,Gill Moulam,Jackie Mutch,Kathleen Parker,Christopher Pawsey,Michelle Purdie,Teresa Robson,Lynne Smith,Carole Stenton,Tom Steuart-Feilding,Beth Stott,Chris Sully,Caroline Sutton,Carol Torrington,Zoe Wilkins,Sharon Williams,Andrea Wilson,Ashleigh Weaver,Peter C. Albertsen,Jan Adolfsson,Michael Baum,Jon McFarlane,Colette Reid,Emma Turner,Anthony L. Zietman,Elizabeth M Hill,Siaw Yein Ng,Naomi J Williams,Jessica Toole,Charlotte F Davies,Laura J Hughes,Mari-Anne Rowlands,Lindsey Bell,Sean Harrison,Jainnee Mauree,Adrian Grant,Ian Roberts,Deborah Ashby,Richard A Cowan,Peter Fayers,Killian Mellon,James N'Dow,Tim O'Brien,Michael Sokhal,David P. Dearnaley,Fritz H. Schröder,Tracy E Roberts +281 more
TL;DR: Analyses according to treatment received showed increased rates of disease-related events and lower rates of patient-reported harms in menmanaged by AM compared with men managed by radical treatment, and stronger evidence of greater PCa mortality in the AM group.
Journal ArticleDOI
Patient-reported outcomes in the ProtecT randomized trial of clinically localized prostate cancer treatments: study design, and baseline urinary, bowel and sexual function and quality of life
Athene Lane,Chris Metcalfe,Grace J. Young,Tim J Peters,Tim J Peters,Jane M Blazeby,Kerry N L Avery,Daniel Dedman,L Down,Malcolm David Mason,David E. Neal,Freddie C. Hamdy,Jenny L Donovan,Jenny L Donovan +13 more
TL;DR: The baseline patient‐reported outcome measures (PROMs) in the Prostate Testing for Cancer and Treatment (ProtecT) randomized trial comparing active monitoring, radical prostatectomy and external‐beam conformal radiotherapy for localized prostate cancer are presented.
Journal ArticleDOI
Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM) for diagnosis and management of bladder outlet obstruction in men: study protocol for a randomised controlled trial
K Bailey,Paul Abrams,Peter S Blair,Christopher R. Chapple,Cathryn Glazener,Jeremy Horwood,J A Lane,John S. McGrath,Sian Noble,Robert Pickard,Gordon T. Taylor,Grace J. Young,Marcus J. Drake,Marcus J. Drake,Amanda L. Lewis +14 more
TL;DR: Whether a care pathway not including invasive urodynamics is no worse for men in terms of symptom outcome than one in which it is included, at 18 months after randomisation is determined.
Journal ArticleDOI
Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT.
Freddie C. Hamdy,Jenny L Donovan,J. Athene Lane,Malcolm David Mason,Chris Metcalfe,Peter Holding,Julia Wade,Sian Noble,Kirsty Garfield,Grace J. Young,Michael Davis,Tim J Peters,Emma L Turner,Richard M. Martin,Jon Oxley,M.C. Robinson,John Staffurth,Eleanor I Walsh,Jane M Blazeby,Richard J. Bryant,Prasad Bollina,James W.F. Catto,Andrew Doble,Alan Doherty,David Gillatt,Vincent J. Gnanapragasam,Owen Hughes,Roger Kockelbergh,Howard Kynaston,Alan Paul,Edgar Paez,Philip Powell,Stephen Prescott,Derek J. Rosario,Edward Rowe,David E. Neal +35 more
TL;DR: A prospective, multicentre prostate-specific antigen testing programme followed by a randomised trial of treatment, with a comprehensive cohort follow-up, to evaluate the effectiveness of conventional treatments for localised prostate cancer in men aged 50-69 years.