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Guanghui Ma

Researcher at Chinese Academy of Sciences

Publications -  519
Citations -  21012

Guanghui Ma is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Membrane emulsification & Antigen. The author has an hindex of 66, co-authored 497 publications receiving 17108 citations. Previous affiliations of Guanghui Ma include Center for Advanced Materials & Nanjing Tech University.

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Novel thermal-sensitive hydrogel enhances both humoral and cell-mediated immune responses by intranasal vaccine delivery.

TL;DR: A novel thermal sensitive hydrogel was formulated with N-[(2-hydroxy-3-trimethylammonium) propyl] chitosan chloride (HTCC) and α, β-glycerophosphate and it displayed low toxicity to nasal tissue and epithelial cells even by frequently intranasal dosing of hydrogels.
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Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment.

TL;DR: Despite multiple immunotherapeutic technologies that achieve potent T cell activation, effector T cells still lack efficiency because of the highly immunosuppressive conditions in the tumor microenvironments as discussed by the authors.
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Multi-stage premix membrane emulsification for preparation of agarose microbeads with uniform size

TL;DR: In this paper, a premix membrane emulsification method was used for the preparation of uniform-sized agarose beads with diameters less than 10 μm and agaroses content as high as 14 wt%.
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Novel vaccine delivery system induces robust humoral and cellular immune responses based on multiple mechanisms.

TL;DR: In vivo investigation shows that Gel MPs, in comparison to aluminum salts, LPS, and covalent cross‐linking quaternized chitosan MPs, induce higher humoral and cellular immune responses with a mixed Th1/Th2 immunity.