Guanghui Ma

TL;DR: The preliminary biological experiment results have verified the efficient photorelease of chlorambucil from B-Cbl-3 and the huge contrast in cytotoxicity between them, superior combined therapeutic performance based on extraordinary low doses of drug and light irradiation, and ratiometric fluorescence imaging for in situ monitoring drug release.

TL;DR: In this paper, two different polymers, poly(vinylbenzyl chloride) and poly(methyl methecrylate-2-hydroxyethyl methacrylate), were respectively employed as the major component of the particle material and amphiphilic polymer methoxy poly (ethylene glycol)-b-poly (D, L-lactide) was employed as an essential additive.

TL;DR: Three-pronged nanoparticles that can efficiently prohibit the proliferation of large tumor are developed for inoperable large tumor therapy and induce the apoptosis of differentiated cancer cells, cancer stem cells, and vascular niches simultaneously.

TL;DR: The potential of the particulate cancer vaccines to recapitalize the inherent host immune responses for the maximum antitumor effect is illustrated and optimized synthetic particles may shed light on the development of safe and effective particulate cancers.

TL;DR: Gel MPs, ionic cross-linked with glycerophosphate (GP), were biocompatible and could efficiently adsorb the inactivated PRRSV vaccine with a loading capacity of 579.05μg/mg and results suggested that Gel MPs elicited significantly higher cell-mediated immune responses and comparable humoral immune responses compared to ISA 206.