G
Guillaume Meurice
Researcher at Institut Gustave Roussy
Publications - 45
Citations - 3092
Guillaume Meurice is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Cancer & Cytotoxic T cell. The author has an hindex of 21, co-authored 44 publications receiving 2503 citations. Previous affiliations of Guillaume Meurice include University of Paris-Sud & Pasteur Institute.
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Journal ArticleDOI
CD8+CD103+ Tumor–Infiltrating Lymphocytes Are Tumor-Specific Tissue-Resident Memory T Cells and a Prognostic Factor for Survival in Lung Cancer Patients
Fayçal Djenidi,Fayçal Djenidi,Fayçal Djenidi,Julien Adam,Julien Adam,Aicha Goubar,Aicha Goubar,Aurélie Durgeau,Aurélie Durgeau,Aurélie Durgeau,Guillaume Meurice,Guillaume Meurice,Vincent de Montpréville,Pierre Validire,Benjamin Besse,Benjamin Besse,Fathia Mami-Chouaib,Fathia Mami-Chouaib,Fathia Mami-Chouaib +18 more
TL;DR: It is shown that an enhanced CD103+ TIL subset correlates with improved early stage NSCLC patient survival and increased intraepithelial lymphocyte infiltration and support the rationale for using anti–PD-1 blocking Ab to reverse tumor-induced T cell exhaustion inNSCLC patients.
Journal ArticleDOI
Genomic characterization of metastatic breast cancers
François Bertucci,Charlotte K.Y. Ng,Charlotte K.Y. Ng,Charlotte K.Y. Ng,Anne Patsouris,Nathalie Droin,Nathalie Droin,Nathalie Droin,Salvatore Piscuoglio,Salvatore Piscuoglio,Nadine Carbuccia,Jean-Charles Soria,Jean-Charles Soria,Alicia Tran Dien,Yahia Adnani,Maud Kamal,Séverine Garnier,Guillaume Meurice,Marta Jimenez,Semih Dogan,Benjamin Verret,Max Chaffanet,Thomas Bachelot,Mario Campone,Claudia Lefeuvre,Hervé Bonnefoi,Florence Dalenc,Alexandra Jacquet,Maria R. De Filippo,Naveen Babbar,Daniel Birnbaum,Thomas Filleron,Christophe Le Tourneau,Christophe Le Tourneau,Christophe Le Tourneau,Fabrice Andre,Fabrice Andre +36 more
TL;DR: The genomic landscape of metastatic breast cancer is enriched in clinically relevant genomic alterations and is more complex than that of early breast cancer.
Journal ArticleDOI
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer
Timothy P. Stinear,Torsten Seemann,Sacha J. Pidot,Wafa Frigui,Gilles Reysset,Thierry Garnier,Guillaume Meurice,David Simon,Christiane Bouchier,Laurence Ma,Magali Tichit,Jessica L. Porter,Janine Ryan,Paul D R Johnson,John K. Davies,Grant A. Jenkin,Pamela L. C. Small,Louis Jones,Fredj Tekaia,Françoise Laval,Mamadou Daffé,Julian Parkhill,Stewart T. Cole +22 more
TL;DR: The complete 5.8-Mb genome sequence of M. ulcerans is reported and indicates that it has recently evolved via lateral gene transfer and reductive evolution from the generalist, more rapid-growing environmental species M. marinum to become a niche-adapted specialist.
Journal ArticleDOI
From a consortium sequence to a unified sequence: The Bacillus subtilis 168 reference genome a decade later
Valérie Barbe,Stéphane Cruveiller,Frank Kunst,Patricia Lenoble,Guillaume Meurice,Agnieszka Sekowska,David Vallenet,Tingzhang Wang,Ivan Moszer,Claudine Médigue,Antoine Danchin +10 more
TL;DR: The updated sequence has been reannotated in agreement with the UniProt protein knowledge base, keeping in perspective the split between the paleome and the cenome, suggesting here that B. subtilis is an epiphyte.
Journal ArticleDOI
Clonal architecture of chronic myelomonocytic leukemias.
Raphael Itzykson,Olivier Kosmider,Aline Renneville,Aline Renneville,Margot Morabito,Margot Morabito,Claude Preudhomme,Claude Preudhomme,Céline Berthon,Lionel Ades,Pierre Fenaux,Uwe Platzbecker,Olivier Gagey,Philippe Rameau,Guillaume Meurice,Cedric Orear,François Delhommeau,Olivier A. Bernard,Michaela Fontenay,William Vainchenker,William Vainchenker,Nathalie Droin,Nathalie Droin,Eric Solary,Eric Solary +24 more
TL;DR: Comparison of clonal expansions of TET2 mutations in MDS, MPN, and CMML, together with functional invalidation of Tet2 in sorted progenitors, suggests a causative link between early clonal dominance and skewed granulomonocytic differentiation.