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Herbert Budka

Researcher at University of Zurich

Publications -  417
Citations -  26786

Herbert Budka is an academic researcher from University of Zurich. The author has contributed to research in topics: Neuropathology & PRNP. The author has an hindex of 85, co-authored 412 publications receiving 25100 citations. Previous affiliations of Herbert Budka include Medical University of Vienna & University of Pécs.

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Scientific Opinion of the Panel on Biological Hazards

TL;DR: In this article, the Biological Hazard Panel is asked to give recommendations for optimising the surveillance and monitoring in humans, animals and foodstuffs and to give advice regarding methods for detection and identification of Toxoplasma from food and animals.
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Prominent corticosteroid disturbance in experimental prion disease.

TL;DR: The concentration of corticosterone metabolites in the faeces of scrapie‐inoculated mice during the course of the clinical disease was determined, and a simultaneous downregulation of cerebral neuronal glucocorticoid receptors was not detectable by immunohistochemistry, indicating that increased corticosteroids can elicit their effects in mouse scrapie freely.
Journal Article

Vascular changes in the cerebral cortex in HIV-1 infection: I. A morphometric investigation by light and electron microscopy.

TL;DR: Using morphometric methods, significant changes of cortical vessels are detectable at the light and electron microscopic level and most probably represent the morphological substrate of an altered blood-brain-barrier in AIDS brains and may account for the reported hypoperfusion demonstrated in SPECT analyses.
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Bilateral striopallidodentate calcification (Fahr's syndrome) and multiple system atrophy in a patient with longstanding hypoparathyroidism.

TL;DR: In this article, a case showing similar neuropathological features in a patient with longstanding hypoparathyroidism was reported, in which one family member was diagnosed with multiple system atrophy at autopsy.
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Pleomorphic xanthoastrocytoma with anaplastic features presenting without GFAP immunoreactivity: implications for differential diagnosis.

TL;DR: It is concluded that non‐standard GFAP staining protocols may enhance sensitivity and thus lead to detection of a low level of GFAP expression in tumor specimens, in which PXA is considered in the differential diagnosis.