H
Herbert Budka
Researcher at University of Zurich
Publications - 417
Citations - 26786
Herbert Budka is an academic researcher from University of Zurich. The author has contributed to research in topics: Neuropathology & PRNP. The author has an hindex of 85, co-authored 412 publications receiving 25100 citations. Previous affiliations of Herbert Budka include Medical University of Vienna & University of Pécs.
Papers
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Journal ArticleDOI
Nail-Patella Syndrome Associated with Respiratory Chain Disorder
TL;DR: This case demonstrates that NPS may be randomly associated with RCD, and NPS patients should undergo detailed cardiological and neurological investigations, in order not to overlook a double trouble partially mimicking NPS.
Journal ArticleDOI
Intraneuronal immunoreactivity for the prion protein distinguishes a subset of E200K genetic from sporadic Creutzfeldt-Jakob Disease.
Gabor G. Kovacs,Kinga Molnár,Eva Keller,Gergő Botond,Gergő Botond,Herbert Budka,Lajos László +6 more
TL;DR: These findings suggest that the permanent production of mutant PrP in the E200K gCJD cases overwhelms the ubiquitin-proteasome system and shifts the balance toward selectivemacroautophagy and/or to ubiquitinated inclusion body and aggresome formation as a cytoprotective effort to sequester the mutant protein.
Journal ArticleDOI
Rabies and herpes simplex virus encephalitis. An immunohistological study on site and distribution of viral antigens.
TL;DR: In the leptomeninges, HSV antigen positive cells were found inconstantly and only in small numbers; this finding makes unlikely the possibility of an intravital diagnosis of HSV encephalitis by immunostaining of cerebrospinal fluid (CSF) cell preparations.
Book ChapterDOI
SSPE-like inclusion body disorder in treated childhood leukemia.
TL;DR: Clinico-pathological report on a boy with cytostatically treated leukemia, dying with cerebral symptoms after passing clinical measles 10 weeks before death, and at autopsy, numerous nuclear inclusion bodies in glial and nerve cells were found suggested a slow type of measles virus infection.
Journal ArticleDOI
Serotonergic nuclei of the raphe are not affected in human ageing.
Stefan Klöppel,Gabor G. Kovacs,Till Voigtländer,Julia Wanschitz,Helga Flicker,Johannes A. Hainfellner,Marin Guentchev,Herbert Budka +7 more
TL;DR: Investigating the serotonergic median raphe nuclei in brains of an older and a younger group found no significant difference between age groups in the percentage of neurons able to synthesize serotonin, suggesting changes might relate to sleep disturbances in the elderly.