H
Herbert Budka
Researcher at University of Zurich
Publications - 417
Citations - 26786
Herbert Budka is an academic researcher from University of Zurich. The author has contributed to research in topics: Neuropathology & PRNP. The author has an hindex of 85, co-authored 412 publications receiving 25100 citations. Previous affiliations of Herbert Budka include Medical University of Vienna & University of Pécs.
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Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
Gabor G. Kovacs,Isidro Ferrer,Irina Alafuzoff,Johannes Attems,Herbert Budka,Nigel J. Cairns,John F. Crary,Charles Duyckaerts,Bernardino Ghetti,Glenda M. Halliday,James W. Ironside,Seth Love,Ian R. A. Mackenzie,David G. Munoz,Melissa E. Murray,Peter T. Nelson,Hitoshi Takahashi,John Q. Trojanowski,Olaf Ansorge,Thomas Arzberger,Atik Baborie,Thomas G. Beach,Kevin F. Bieniek,Eileen H. Bigio,Istvan Bodi,Brittany N. Dugger,Mel B. Feany,Ellen Gelpi,Stephen M. Gentleman,Giorgio Giaccone,Kimmo J. Hatanpaa,Richard Heale,Patrick R. Hof,Monika Hofer,Tibor Hortobágyi,Kurt A. Jellinger,Gregory A. Jicha,Paul G. Ince,Julia Kofler,Eniko Veronika Kovari,Jillian J. Kril,David M. A. Mann,Radoslav Matej,Ann C. McKee,Catriona McLean,Ivan Milenkovic,Thomas J. Montine,Shigeo Murayama,Edward B. Lee,Jasmin Rahimi,Roberta Diehl Rodriguez,Annemieke J.M. Rozemuller,Julie A. Schneider,Christian Schultz,William W. Seeley,Danielle Seilhean,Colin Smith,Fabrizio Tagliavini,Masaki Takao,Dietmar Rudolf Thal,Jon B. Toledo,Markus Tolnay,Juan C. Troncoso,Harry V. Vinters,Serge Weis,Stephen B. Wharton,Charles L. White,Thomas Wisniewski,John Woulfe,Masahito Yamada,Dennis W. Dicks +70 more
TL;DR: The goal of this proposal is to raise awareness of astroglial tau pathology in the aged brain, facilitating communication among neuropathologists and researchers, and informing interpretation of clinical biomarkers and imaging studies that focus on tau-related indicators.
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Multinucleated giant cells in brain: a hallmark of the acquired immune deficiency syndrome (AIDS).
TL;DR: The formation of MGCs is likely to represent a cytopathic effect of the virus on lymphoid or mono-histiocytic cells infiltrating the brain (infection of these cells could occur before or after they entered the brain).
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TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea†
Gabor G. Kovacs,Gabor G. Kovacs,Jill R. Murrell,Sandor Horvath,Laszlo Haraszti,Katalin Majtényi,Mária Judit Molnár,Herbert Budka,Bernardino Ghetti,Salvatore Spina,Salvatore Spina +10 more
TL;DR: Clinopathological and genetic findings in a carrier of the novel K263E TARDBP variation, who developed frontotemporal dementia, supranuclear palsy, and chorea, but no signs of motor neuron disease are described.
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Peroxisomal alterations in Alzheimer's disease
Jianqiu Kou,Gabor G. Kovacs,Romana Höftberger,Willem Kulik,Alexander Brodde,Sonja Forss-Petter,Selma Hönigschnabl,Andreas Gleiss,Britta Brügger,Ronald J.A. Wanders,Wilhelm W. Just,Herbert Budka,Susanne Jungwirth,Peter Fischer,Johannes Berger +14 more
TL;DR: Substantial peroxisome-related alterations in AD may contribute to the progression of AD pathology, and the decrease in plasmalogens and the increase in VLCFA andperoxisomal volume density in neuronal somata all showed a stronger association with NFT than with neuritic plaques.
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Neuropathology of prion diseases
TL;DR: New patterns of PrP(Sc) immunoreactivity include granular ganglionic and tiny adaxonal PrP (Sc) deposits in peripheral nervous tissue, and dendritic cells and macrophages in vessel walls, suggesting that mobile haematogenous cells may be involved in spread of prions.