H
Herbert Budka
Researcher at University of Zurich
Publications - 417
Citations - 26786
Herbert Budka is an academic researcher from University of Zurich. The author has contributed to research in topics: Neuropathology & PRNP. The author has an hindex of 85, co-authored 412 publications receiving 25100 citations. Previous affiliations of Herbert Budka include Medical University of Vienna & University of Pécs.
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Journal ArticleDOI
Immunohistochemical Analysis of Platelet-derived Growth Factor Receptor-α, -β, c-kit, c-abl, and Arg Proteins in Glioblastoma: Possible Implications for Patient Selection for Imatinib Mesylate Therapy
Christine Haberler,Ellen Gelpi,Christine Marosi,Karl Rössler,Peter Birner,Herbert Budka,J. A. Hainfellner,J. A. Hainfellner +7 more
TL;DR: It is shown here for the first time in a large series of glioblastomas that PDGFR-α, -β, c-kit,c-abl and arg expression is immunohistochemically detectable in a fraction of cases.
Journal Article
Pseudogliomatous growth pattern of anaplastic small cell carcinomas metastatic to the brain
Neves S,Peter R. Mazal,Wanschitz J,Rudnay Ac,M. Drlicek,Thomas Czech,Wüstinger C,Herbert Budka +7 more
TL;DR: A systematic study of the growth pattern of cerebral metastases, focusing on tumor delineation, observed poorly defined borders and a highly diffuse pattern of invasion in 26 cases of 66 metastatic anaplastic small cell carcinomas and in one case of adenocarcinoma.
Journal ArticleDOI
Progressive multifocal leukoencephalopathy (PML) in AIDS and in the pre-AIDS era. A neuropathological comparison using immunocytochemistry and in situ DNA hybridization for virus detection.
TL;DR: It is concluded that ICC and ISH are methods of comparable sensitivity for detection of papovavirus in flourishing PML lesions only ISH may detect virus in burnt-outPML lesions.
Journal ArticleDOI
Accumulation of 14-3-3 proteins in glial cytoplasmic inclusions in multiple system atrophy.
TL;DR: The results suggest that an aberrant accumulation of 14‐3‐3 proteins may occur in brains affected by multiple system atrophy, and that 14‐ 3‐3protein may be associated with the pathogenesis of multiple systematrophy.
Journal Article
Tau and ubiquitin immunoreactivity at different stages of formation of Alzheimer neurofibrillary tangles.
Christian Bancher,C. Brunner,Hans Lassmann,Herbert Budka,Kurt A. Jellinger,F. Seitelberger,Inge Grundke-Iqbal,Khalid Iqbal,Henryk M. Wisniewski +8 more
TL;DR: In this study, immunoreactivity for the altered tau is not only seen in a subset of tangles but also in the cytoplasm of some nerve cells lacking ANT, which is believed to be at a stage of neuronal alteration preceding the formation of compact tangles (Stage 0 tangles).